Cargando…

Astilbin prevents osteoarthritis development through the TLR4/MD‐2 pathway

Osteoarthritis has become one of the main diseases affecting the life of many elderly people with high incidence of disability, and local chronic inflammation in the joint cavity is the most crucial pathological feature of osteoarthritis. Astilbin is the main active component in a variety of natural...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Shuaibo, Yan, Zijian, Shui, Xiaolong, Qi, Weihui, Chen, Yanlin, Xu, Xinxian, Hu, Yuezheng, Guo, Weijun, Shang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701562/ https://www.ncbi.nlm.nih.gov/pubmed/33063931 http://dx.doi.org/10.1111/jcmm.15915

Ejemplares similares

Inhibiting TLR4 signaling by linarin for preventing inflammatory response in osteoarthritis
por: Qi, Weihui, et al.
Publicado: (2021)

Astilbin-induced inhibition of the PI3K/AKT signaling pathway decelerates the progression of osteoarthritis
por: Chen, Chunlin, et al.
Publicado: (2020)

Molecular Insight into the Binding of Astilbin with Human Serum Albumin and Its Effect on Antioxidant Characteristics of Astilbin
por: Han, Xiangyu, et al.
Publicado: (2022)

Procyanidin B3 alleviates intervertebral disc degeneration via interaction with the TLR4/MD‐2 complex
por: Shang, Ping, et al.
Publicado: (2020)

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis
por: Jin, Haiming, et al.
Publicado: (2019)

Astilbin influences the progression of osteoarthritis in rats by down-regulation of PGE-2 expression via the NF-κB pathway
por: Yang, Mao, et al.
Publicado: (2020)

Astilbin Inhibits the Activity of Sortase A from Streptococcus mutans
por: Wang, Junxian, et al.
Publicado: (2019)

Astilbin Inhibits High Glucose-Induced Inflammation and Extracellular Matrix Accumulation by Suppressing the TLR4/MyD88/NF-κB Pathway in Rat Glomerular Mesangial Cells
por: Chen, Fang, et al.
Publicado: (2018)

A Comparison of Solubility, Stability, and Bioavailability between Astilbin and Neoastilbin Isolated from Smilax glabra Rhizoma
por: Zheng, Dan, et al.
Publicado: (2020)

Astilbin reduces ROS accumulation and VEGF expression through Nrf2 in psoriasis-like skin disease
por: Wang, Wuyuntana, et al.
Publicado: (2019)

Study of pro-angiogenic activity of astilbin on human umbilical vein endothelial cells in vitro and zebrafish in vivo
por: Lv, Kongpeng, et al.
Publicado: (2019)

Partially Glycosylated Dendrimers Block MD-2 and Prevent TLR4-MD-2-LPS Complex Mediated Cytokine Responses
por: Barata, Teresa S., et al.
Publicado: (2011)

Astilbin from Smilax glabra Roxb. Attenuates Inflammatory Responses in Complete Freund's Adjuvant-Induced Arthritis Rats
por: Dong, Lisha, et al.
Publicado: (2017)

Regulatory network of two circRNAs and an miRNA with their targeted genes under astilbin treatment in pulmonary fibrosis
por: Lu, Guangping, et al.
Publicado: (2019)

Characterizing the binding interaction of astilbin with bovine serum albumin: a spectroscopic study in combination with molecular docking technology
por: Liu, Jianli, et al.
Publicado: (2018)

Alpha-glucosidase inhibitory activities of astilbin contained in Bauhinia strychnifolia Craib. stems: an investigation by in silico and in vitro studies
por: Eawsakul, Komgrit, et al.
Publicado: (2023)

Decrease of Functional Activated T and B Cells and Treatment of Glomerulonephitis in Lupus-Prone Mice Using a Natural Flavonoid Astilbin
por: Guo, Lele, et al.
Publicado: (2015)

Corrigendum to “Astilbin from Smilax glabra Roxb. Attenuates Inflammatory Responses in Complete Freund's Adjuvant-Induced Arthritis Rats”
por: Dong, Lisha, et al.
Publicado: (2018)

Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling
por: Huang, Dabin, et al.
Publicado: (2022)

Smilax aristolochiifolia Root Extract and Its Compounds Chlorogenic Acid and Astilbin Inhibit the Activity of α-Amylase and α-Glucosidase Enzymes
por: Pérez-Nájera, Viridiana Candelaria, et al.
Publicado: (2018)

Antioxidant and In Vivo Hypoglycemic Activities of Ethanol Extract from the Leaves of Engelhardia roxburghiana Wall, a Comparative Study of the Extract and Astilbin
por: Guo, Xiaoqiang, et al.
Publicado: (2023)

Identification of a Heme Activation Site on the MD-2/TLR4 Complex
por: Belcher, John D., et al.
Publicado: (2020)

Activating Nrf2 signalling alleviates osteoarthritis development by inhibiting inflammasome activation
por: Yan, Zijian, et al.
Publicado: (2020)

Identification of key genes and pathways associated with sex difference in osteoarthritis based on bioinformatics analysis
por: Xu, Junchang, et al.
Publicado: (2022)

Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis
por: Rajamanickam, Vinothkumar, et al.
Publicado: (2020)

Inefficient TLR4/MD-2 Heterotetramerization by Monophosphoryl Lipid A
por: Casella, Carolyn R., et al.
Publicado: (2013)

TLR4/MD-2 is a receptor for extracellular nucleophosmin 1
por: Nakatomi, Kota, et al.
Publicado: (2021)

Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4(+) T Cell Activities via Direct Binding With Cytochrome P450 1B1
por: Ding, Shizhen, et al.
Publicado: (2022)

Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis: Erratum
por: Rajamanickam, Vinothkumar, et al.
Publicado: (2022)

Recognition of lipid A variants by the TLR4-MD-2 receptor complex
por: Maeshima, Nina, et al.
Publicado: (2013)

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling
por: Yang, Huan, et al.
Publicado: (2015)

MD-2 Determinants of Nickel and Cobalt-Mediated Activation of Human TLR4
por: Oblak, Alja, et al.
Publicado: (2015)

Lycopene inhibits IL‐1β‐induced inflammation in mouse chondrocytes and mediates murine osteoarthritis
por: Zhan, Jingdi, et al.
Publicado: (2021)

The Effects of Oral and Enteric Campylobacter concisus Strains on Expression of TLR4, MD-2, TLR2, TLR5 and COX-2 in HT-29 Cells
por: Ismail, Yazan, et al.
Publicado: (2013)

Epimedium sagittatum inhibits TLR4/MD-2 mediated NF-κB signaling pathway with anti-inflammatory activity
por: Yan, Ni, et al.
Publicado: (2018)

LPS-induced CXCR7 expression promotes gastric Cancer proliferation and migration via the TLR4/MD-2 pathway
por: Li, Nan, et al.
Publicado: (2019)

A Single Step in vitro Bioassay Mimicking TLR4-LPS Pathway and the Role of MD2 and CD14 Coreceptors
por: Jagtap, Pramod, et al.
Publicado: (2020)

Topical astilbin ameliorates imiquimod‐induced psoriasis‐like skin lesions in SKH‐1 mice via suppression dendritic cell‐Th17 inflammation axis
por: Xu, Qingqing, et al.
Publicado: (2022)

Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling
por: Li, Hongyuan, et al.
Publicado: (2021)

Demethyleneberberine alleviated the inflammatory response by targeting MD-2 to inhibit the TLR4 signaling
por: Zhao, Yaxing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qg5772r9da7p3c394rhq4qo9ef