Doxorubicin hydrochloride enhanced antitumour effect of CEA‐regulated oncolytic virotherapy in live cancer cells and a mouse model

Oncolytic adenovirus (OA) has attracted increasing attention due to their specific proliferation in tumour cells and resulting in lysis of tumour cells. To further improve the antitumour effect of OA, in this study, we combined CD55‐TRAIL‐IETD‐MnSOD (CD55‐TMn), a CEA‐controlled OA constructed previo...

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Detalles Bibliográficos
Autores principales: Xiao, Boduan, Ying, Chang, Chen, Yongyi, Huang, Fang, Wang, Binrong, Fang, Huiling, Guo, Wan, Liu, Tao, Zhou, Xiumei, Huang, Biao, Liu, Xinyuan, Wang, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701578/
https://www.ncbi.nlm.nih.gov/pubmed/33251723
http://dx.doi.org/10.1111/jcmm.15966

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