Cargando…
Calhex231 ameliorates myocardial fibrosis post myocardial infarction in rats through the autophagy‐NLRP3 inflammasome pathway in macrophages
The calcium‐sensing receptor (CaSR) is involved in the pathophysiology of many cardiovascular diseases, including myocardial infarction (MI) and hypertension. The role of Calhex231, a specific inhibitor of CaSR, in myocardial fibrosis following MI is still unclear. Using Wistar rats, we investigated...
Autores principales: | Liu, Wenxiu, Sun, Jiaxing, Guo, Yutong, Liu, Na, Ding, Xue, Zhang, Xin, Chi, Jinyu, Kang, Ningning, Liu, Yue, Yin, Xinhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701583/ https://www.ncbi.nlm.nih.gov/pubmed/33043596 http://dx.doi.org/10.1111/jcmm.15969 |
Ejemplares similares
-
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats
por: Nie, Chaoqun, et al.
Publicado: (2021) -
The Role of Autophagy and NLRP3 Inflammasome in Liver Fibrosis
por: Tao, Ye, et al.
Publicado: (2020) -
The Calcilytic Drug Calhex-231 Ameliorates Vascular Hyporesponsiveness in Traumatic Hemorrhagic Shock by Inhibiting Oxidative Stress and miR-208a-Mediated Mitochondrial Fission
por: Lei, Yan, et al.
Publicado: (2020) -
LuQi Formula Ameliorates Myocardial Fibrosis by Suppressing TLR4/MyD88/NF-κB Pathway and NLRP3 Inflammasome Activation in Mice with Myocardial Infarction
por: Zhang, Xiaoqing, et al.
Publicado: (2022) -
The Possible Role of NLRP3 Inflammasome in Depression and Myocardial Infarction Comorbidity
por: Baysak, Erensu, et al.
Publicado: (2023)