Cargando…

Calhex231 ameliorates myocardial fibrosis post myocardial infarction in rats through the autophagy‐NLRP3 inflammasome pathway in macrophages

The calcium‐sensing receptor (CaSR) is involved in the pathophysiology of many cardiovascular diseases, including myocardial infarction (MI) and hypertension. The role of Calhex231, a specific inhibitor of CaSR, in myocardial fibrosis following MI is still unclear. Using Wistar rats, we investigated...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wenxiu, Sun, Jiaxing, Guo, Yutong, Liu, Na, Ding, Xue, Zhang, Xin, Chi, Jinyu, Kang, Ningning, Liu, Yue, Yin, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701583/
https://www.ncbi.nlm.nih.gov/pubmed/33043596
http://dx.doi.org/10.1111/jcmm.15969

Ejemplares similares