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Loss of TG‐Interacting Factor 1 decreases survival in mouse models of myeloid leukaemia
TG‐Interacting Factor 1 (Tgif1) affects proliferation and differentiation of myeloid cells and regulates self‐renewal of haematopoietic stem cells (HSCs). To determine its impact on leukaemic haematopoiesis, we induced acute or chronic myeloid leukaemias (AML or CML) in mice by enforced expression o...
Autores principales: | Yan, Ling, Davé, Utpal P., Engel, Michael, Brandt, Stephen J., Hamid, Rizwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701585/ https://www.ncbi.nlm.nih.gov/pubmed/33058427 http://dx.doi.org/10.1111/jcmm.15977 |
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