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Loss of TG‐Interacting Factor 1 decreases survival in mouse models of myeloid leukaemia

TG‐Interacting Factor 1 (Tgif1) affects proliferation and differentiation of myeloid cells and regulates self‐renewal of haematopoietic stem cells (HSCs). To determine its impact on leukaemic haematopoiesis, we induced acute or chronic myeloid leukaemias (AML or CML) in mice by enforced expression o...

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Detalles Bibliográficos
Autores principales: Yan, Ling, Davé, Utpal P., Engel, Michael, Brandt, Stephen J., Hamid, Rizwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701585/
https://www.ncbi.nlm.nih.gov/pubmed/33058427
http://dx.doi.org/10.1111/jcmm.15977

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