CIGAR‐seq, a CRISPR/Cas‐based method for unbiased screening of novel mRNA modification regulators

Cellular RNA is decorated with over 170 types of chemical modifications. Many modifications in mRNA, including m(6)A and m(5)C, have been associated with critical cellular functions under physiological and/or pathological conditions. To understand the biological functions of these modifications, it...

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Detalles Bibliográficos
Autores principales: Fang, Liang, Wang, Wen, Li, Guipeng, Zhang, Li, Li, Jun, Gan, Diwen, Yang, Jiao, Tang, Yisen, Ding, Zewen, Zhang, Min, Zhang, Wenhao, Deng, Daqi, Song, Zhengyu, Zhu, Qionghua, Cui, Huanhuan, Hu, Yuhui, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701898/
https://www.ncbi.nlm.nih.gov/pubmed/33251765
http://dx.doi.org/10.15252/msb.202010025

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