Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report

Perineal seeding of tumor cells from prostate cancer (PCa) is very rare, and no standard treatment exists for this atypical presentation with no evidence of distant metastases. Local excision or external beam radiotherapy are used as local salvage treatments for such perineal masses, including those...

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Detalles Bibliográficos
Autores principales: Vavassori, Andrea, Durante, Stefano, Augugliaro, Matteo, Comi, Stefania, Cambria, Raffaella, Cattani, Federica, Lazzari, Roberta, Matei, Deliu Victor, Cobelli, Ottavio De, Orecchia, Roberto, Jereczek-Fossa, Barbara Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701923/
https://www.ncbi.nlm.nih.gov/pubmed/33299439
http://dx.doi.org/10.5114/jcb.2020.100383
Descripción
Sumario:Perineal seeding of tumor cells from prostate cancer (PCa) is very rare, and no standard treatment exists for this atypical presentation with no evidence of distant metastases. Local excision or external beam radiotherapy are used as local salvage treatments for such perineal masses, including those occurring after biopsy, surgery, or interstitial brachytherapy. We report on a patient who presented no evidence of disease and no late urinary or gastrointestinal toxicities at 58 months after receiving high-dose-rate brachytherapy (HDR-BT) for perineal recurrence of PCa after radical prostatectomy and salvage external beam radiotherapy. To the best of our knowledge, this is the first case treated with HDR-BT in this scenario.

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