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Nrl Is Dispensable for Specification of Rod Photoreceptors in Adult Zebrafish Despite Its Deeply Conserved Requirement Earlier in Ontogeny

The transcription factor NRL (neural retina leucine zipper) has been canonized as the master regulator of photoreceptor cell fate in the retina. NRL is necessary and sufficient to specify rod cell fate and to preclude cone cell fate in mice. By engineering zebrafish, we tested if NRL function has co...

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Detalles Bibliográficos
Autores principales: Oel, A. Phillip, Neil, Gavin J., Dong, Emily M., Balay, Spencer D., Collett, Keon, Allison, W. Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702016/
https://www.ncbi.nlm.nih.gov/pubmed/33299975
http://dx.doi.org/10.1016/j.isci.2020.101805