Cargando…

Nrl Is Dispensable for Specification of Rod Photoreceptors in Adult Zebrafish Despite Its Deeply Conserved Requirement Earlier in Ontogeny

The transcription factor NRL (neural retina leucine zipper) has been canonized as the master regulator of photoreceptor cell fate in the retina. NRL is necessary and sufficient to specify rod cell fate and to preclude cone cell fate in mice. By engineering zebrafish, we tested if NRL function has co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oel, A. Phillip, Neil, Gavin J., Dong, Emily M., Balay, Spencer D., Collett, Keon, Allison, W. Ted
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702016/ https://www.ncbi.nlm.nih.gov/pubmed/33299975 http://dx.doi.org/10.1016/j.isci.2020.101805

Ejemplares similares

Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL
por: Zelinger, Lina, et al.
Publicado: (2017)

Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration
por: Liu, Fei, et al.
Publicado: (2022)

Transcriptional Regulation of Rod Photoreceptor Homeostasis Revealed by In Vivo NRL Targetome Analysis
por: Hao, Hong, et al.
Publicado: (2012)

Abnormal Cone and Rod Photoreceptor Morphogenesis in gdf6a Mutant Zebrafish
por: Nadolski, Nathan J., et al.
Publicado: (2020)

Nrl:CreERT2 mouse model to induce mosaic gene expression in rod photoreceptors
por: Thorson, Molly T., et al.
Publicado: (2023)

gdf6a Is Required for Cone Photoreceptor Subtype Differentiation and for the Actions of tbx2b in Determining Rod Versus Cone Photoreceptor Fate
por: DuVal, Michèle G., et al.
Publicado: (2014)

NRL(−/−) gene edited human embryonic stem cells generate rod‐deficient retinal organoids enriched in S‐cone‐like photoreceptors
por: Cuevas, Elisa, et al.
Publicado: (2021)

Transcripts within rod photoreceptors of the Zebrafish retina
por: Sun, Chi, et al.
Publicado: (2018)

Investigating cone photoreceptor development using patient-derived NRL null retinal organoids
por: Kallman, Alyssa, et al.
Publicado: (2020)

Generation of a rod-specific NRL reporter line in human pluripotent stem cells
por: Phillips, M. Joseph, et al.
Publicado: (2018)

NRL plasma formulary
por: Book, David L
Publicado: (1983)

Photoreceptors of Nrl (−/−) Mice Coexpress Functional S- and M-cone Opsins Having Distinct Inactivation Mechanisms
por: Nikonov, Sergei S., et al.
Publicado: (2005)

Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish
por: Liu, Yuan, et al.
Publicado: (2015)

Expression patterns of zebrafish nocturnin genes and the transcriptional activity of the frog nocturnin promoter in zebrafish rod photoreceptors
por: Yang, Xiaojun, et al.
Publicado: (2017)

Identification of Nrl1 Domains Responsible for Interactions with RNA-Processing Factors and Regulation of Nrl1 Function by Phosphorylation
por: Mikolaskova, Barbora, et al.
Publicado: (2021)

Targeting of the NRL Pathway as a Therapeutic Strategy to Treat Retinitis Pigmentosa
por: Moore, Spencer M., et al.
Publicado: (2020)

Phosphodiesterase Inhibitors Sildenafil and Vardenafil Reduce Zebrafish Rod Photoreceptor Outer Segment Shedding
por: Campbell, Leah J., et al.
Publicado: (2017)

Targeted disruption of the endogenous zebrafish rhodopsin locus as models of rapid rod photoreceptor degeneration
por: Zelinka, Christopher P., et al.
Publicado: (2018)

A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors
por: Santhanam, Abirami, et al.
Publicado: (2020)

Zebrafish Models of Photoreceptor Dysfunction and Degeneration
por: Noel, Nicole C. L., et al.
Publicado: (2021)

Modeling Podocyte Ontogeny and Podocytopathies with the Zebrafish
por: Drummond, Bridgette E., et al.
Publicado: (2023)

THE ULTRASTRUCTURE OF LIPID-DEPLETED ROD PHOTORECEPTOR MEMBRANES
por: Nir, Izhak, et al.
Publicado: (1974)

Ionizable groups and conductances of the rod photoreceptor membrane
por: Pinto, LH, et al.
Publicado: (1978)

Resonance Raman microscopy of rod and cone photoreceptors
Publicado: (1982)

Transduction Gain in Light Adaptation of Rod Photoreceptors
por: Pepperberg, David R.
Publicado: (2001)

Rod Bipolar Cells Require Horizontal Cells for Invagination Into the Terminals of Rod Photoreceptors
por: Nemitz, Lena, et al.
Publicado: (2019)

Capillary Optical Guiding Experiments for the NRL Laser Wakefield Accelerator
por: Jones, T G, et al.
Publicado: (2001)

Autosomal Recessive NRL Mutations in Patients with Enhanced S-Cone Syndrome
por: Littink, Karin W., et al.
Publicado: (2018)

PRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptors
por: Morrissey, Maria E, et al.
Publicado: (2011)

THE OSMOTIC BEHAVIOR OF ROD PHOTORECEPTOR OUTER SEGMENT DISCS
por: Heller, Joram, et al.
Publicado: (1971)

Characterization of the retinal proteome during rod photoreceptor genesis
por: Barnhill, Alison E, et al.
Publicado: (2010)

Adaptive potentiation in rod photoreceptors after light exposure
por: McKeown, Alex S., et al.
Publicado: (2014)

Advances in repairing the degenerate retina by rod photoreceptor transplantation()
por: Pearson, Rachael A.
Publicado: (2014)

The discovery of the ability of rod photoreceptors to signal single photons
por: Pugh, Edward N.
Publicado: (2018)

The mechanism of photon-like dark noise in rod photoreceptors
por: Pugh, Edward N.
Publicado: (2019)

Modeling and simulation of phototransduction cascade in vertebrate rod photoreceptors
por: Pan, Guofeng, et al.
Publicado: (2019)

Adaptation memory in photoreceptors: different mechanisms in rods and cones
por: Nikolaeva, Darya A., et al.
Publicado: (2023)

Origin of Discrete and Continuous Dark Noise in Rod Photoreceptors
por: Bocchero, Ulisse, et al.
Publicado: (2023)

Defects in the Outer Limiting Membrane Are Associated with Rosette Development in the Nrl(−/−) Retina
por: Stuck, Michael W., et al.
Publicado: (2012)

LsNRL4 enhances photosynthesis and decreases leaf angles in lettuce
por: An, Guanghui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_evpsm18rudii4ol4rdl31lcj7e