Neutrophil Elastase Facilitates Tumor Cell Intravasation and Early Metastatic Events

Functional roles of neutrophil elastase (NE) have not been examined in distinct steps of the metastatic cascade. NE, delivered to primary tumors as a purified enzyme or within intact neutrophils or neutrophil granule content, enhanced human tumor cell intravasation and subsequent dissemination via N...

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Detalles Bibliográficos
Autores principales: Deryugina, Elena, Carré, Alexia, Ardi, Veronica, Muramatsu, Tomoki, Schmidt, Jonas, Pham, Christine, Quigley, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702017/
https://www.ncbi.nlm.nih.gov/pubmed/33299970
http://dx.doi.org/10.1016/j.isci.2020.101799

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