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Immune‐Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2–Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury

BACKGROUND AND AIMS: Itaconate, a metabolite of the tricarboxylic acid cycle, plays anti‐inflammatory roles in macrophages during endotoxemia. The mechanisms underlying its anti‐inflammatory roles have been shown to be mediated by the modulation of oxidative stress, an important mechanism of hepatic...

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Detalles Bibliográficos
Autores principales:	Yi, Zhongjie, Deng, Meihong, Scott, Melanie J., Fu, Guang, Loughran, Patricia A., Lei, Zhao, Li, Shilai, Sun, Ping, Yang, Chenxuan, Li, Wenbo, Xu, Hongbo, Huang, Feizhou, Billiar, Timothy R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702080/ https://www.ncbi.nlm.nih.gov/pubmed/31997373 http://dx.doi.org/10.1002/hep.31147

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