Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants

To meet increasing global food demand, breeders and scientists aim to improve the yield and quality of major food crops. Plant diseases threaten food security and are expected to increase because of climate change. CRISPR genome-editing technology opens new opportunities to engineer disease resistan...

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Autores principales: Zaidi, Syed Shan-e-Ali, Mahas, Ahmed, Vanderschuren, Hervé, Mahfouz, Magdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702697/
https://www.ncbi.nlm.nih.gov/pubmed/33256828
http://dx.doi.org/10.1186/s13059-020-02204-y
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author Zaidi, Syed Shan-e-Ali
Mahas, Ahmed
Vanderschuren, Hervé
Mahfouz, Magdy M.
author_facet Zaidi, Syed Shan-e-Ali
Mahas, Ahmed
Vanderschuren, Hervé
Mahfouz, Magdy M.
author_sort Zaidi, Syed Shan-e-Ali
collection PubMed
description To meet increasing global food demand, breeders and scientists aim to improve the yield and quality of major food crops. Plant diseases threaten food security and are expected to increase because of climate change. CRISPR genome-editing technology opens new opportunities to engineer disease resistance traits. With precise genome engineering and transgene-free applications, CRISPR is expected to resolve the major challenges to crop improvement. Here, we discuss the latest developments in CRISPR technologies for engineering resistance to viruses, bacteria, fungi, and pests. We conclude by highlighting current concerns and gaps in technology, as well as outstanding questions for future research.
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spelling pubmed-77026972020-12-01 Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants Zaidi, Syed Shan-e-Ali Mahas, Ahmed Vanderschuren, Hervé Mahfouz, Magdy M. Genome Biol Review To meet increasing global food demand, breeders and scientists aim to improve the yield and quality of major food crops. Plant diseases threaten food security and are expected to increase because of climate change. CRISPR genome-editing technology opens new opportunities to engineer disease resistance traits. With precise genome engineering and transgene-free applications, CRISPR is expected to resolve the major challenges to crop improvement. Here, we discuss the latest developments in CRISPR technologies for engineering resistance to viruses, bacteria, fungi, and pests. We conclude by highlighting current concerns and gaps in technology, as well as outstanding questions for future research. BioMed Central 2020-11-30 /pmc/articles/PMC7702697/ /pubmed/33256828 http://dx.doi.org/10.1186/s13059-020-02204-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Zaidi, Syed Shan-e-Ali
Mahas, Ahmed
Vanderschuren, Hervé
Mahfouz, Magdy M.
Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
title Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
title_full Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
title_fullStr Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
title_full_unstemmed Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
title_short Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
title_sort engineering crops of the future: crispr approaches to develop climate-resilient and disease-resistant plants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702697/
https://www.ncbi.nlm.nih.gov/pubmed/33256828
http://dx.doi.org/10.1186/s13059-020-02204-y
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