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Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging

OBJECTIVES: To investigate the clinical value of non-invasive ultrasound imaging in the evaluation of brain death caused by traumatic brain injury. METHODS: Thirty-four patients with acute severe traumatic brain injury were admitted to hospital within 48 h after injury. All patients were monitored i...

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Autores principales: Niu, Ningning, Tang, Ying, Hao, Xiaoye, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702728/
https://www.ncbi.nlm.nih.gov/pubmed/33312121
http://dx.doi.org/10.3389/fninf.2020.607365
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author Niu, Ningning
Tang, Ying
Hao, Xiaoye
Wang, Jing
author_facet Niu, Ningning
Tang, Ying
Hao, Xiaoye
Wang, Jing
author_sort Niu, Ningning
collection PubMed
description OBJECTIVES: To investigate the clinical value of non-invasive ultrasound imaging in the evaluation of brain death caused by traumatic brain injury. METHODS: Thirty-four patients with acute severe traumatic brain injury were admitted to hospital within 48 h after injury. All patients were monitored intracranial pressure, transcranial Doppler, echocardiography examination, collection intracranial pressure, MCA-Vs, MCA-Vd, MCA-Vm, EF, LVMPI, RVMPI and other indicators, and combined with clinical conditions and other related data for comparative study and statistical analysis. RESULTS: The blood flow spectrum was characterized by diastolic retrograde blood flow spectrum pattern and nail waveform spectrum shape when the patient had clinical brain death. For the parameters of transcranial Doppler, there were significant differences in MCA-Vm and PI between clinical brain death group and normal control group (P < 0.05). For the parameters of echocardiography, there were statistically significant differences in EF, LVMPI, and RVMPI between clinical brain death group and normal control group (P < 0.05). CONCLUSION: Non-invasive dynamic monitoring of cerebral hemodynamics and cardiac function parameters in patients with severe craniocerebral injury can provide a high accuracy and reliability for the preliminary diagnosis of brain death in patients with severe craniocerebral injury. It is helpful for early evaluation of prognosis and provides effective monitoring methods and guidance for clinical treatment.
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spelling pubmed-77027282020-12-10 Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging Niu, Ningning Tang, Ying Hao, Xiaoye Wang, Jing Front Neuroinform Neuroscience OBJECTIVES: To investigate the clinical value of non-invasive ultrasound imaging in the evaluation of brain death caused by traumatic brain injury. METHODS: Thirty-four patients with acute severe traumatic brain injury were admitted to hospital within 48 h after injury. All patients were monitored intracranial pressure, transcranial Doppler, echocardiography examination, collection intracranial pressure, MCA-Vs, MCA-Vd, MCA-Vm, EF, LVMPI, RVMPI and other indicators, and combined with clinical conditions and other related data for comparative study and statistical analysis. RESULTS: The blood flow spectrum was characterized by diastolic retrograde blood flow spectrum pattern and nail waveform spectrum shape when the patient had clinical brain death. For the parameters of transcranial Doppler, there were significant differences in MCA-Vm and PI between clinical brain death group and normal control group (P < 0.05). For the parameters of echocardiography, there were statistically significant differences in EF, LVMPI, and RVMPI between clinical brain death group and normal control group (P < 0.05). CONCLUSION: Non-invasive dynamic monitoring of cerebral hemodynamics and cardiac function parameters in patients with severe craniocerebral injury can provide a high accuracy and reliability for the preliminary diagnosis of brain death in patients with severe craniocerebral injury. It is helpful for early evaluation of prognosis and provides effective monitoring methods and guidance for clinical treatment. Frontiers Media S.A. 2020-11-16 /pmc/articles/PMC7702728/ /pubmed/33312121 http://dx.doi.org/10.3389/fninf.2020.607365 Text en Copyright © 2020 Niu, Tang, Hao and Wang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Niu, Ningning
Tang, Ying
Hao, Xiaoye
Wang, Jing
Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging
title Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging
title_full Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging
title_fullStr Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging
title_full_unstemmed Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging
title_short Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging
title_sort non-invasive evaluation of brain death caused by traumatic brain injury by ultrasound imaging
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702728/
https://www.ncbi.nlm.nih.gov/pubmed/33312121
http://dx.doi.org/10.3389/fninf.2020.607365
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