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Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging
OBJECTIVES: To investigate the clinical value of non-invasive ultrasound imaging in the evaluation of brain death caused by traumatic brain injury. METHODS: Thirty-four patients with acute severe traumatic brain injury were admitted to hospital within 48 h after injury. All patients were monitored i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702728/ https://www.ncbi.nlm.nih.gov/pubmed/33312121 http://dx.doi.org/10.3389/fninf.2020.607365 |
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author | Niu, Ningning Tang, Ying Hao, Xiaoye Wang, Jing |
author_facet | Niu, Ningning Tang, Ying Hao, Xiaoye Wang, Jing |
author_sort | Niu, Ningning |
collection | PubMed |
description | OBJECTIVES: To investigate the clinical value of non-invasive ultrasound imaging in the evaluation of brain death caused by traumatic brain injury. METHODS: Thirty-four patients with acute severe traumatic brain injury were admitted to hospital within 48 h after injury. All patients were monitored intracranial pressure, transcranial Doppler, echocardiography examination, collection intracranial pressure, MCA-Vs, MCA-Vd, MCA-Vm, EF, LVMPI, RVMPI and other indicators, and combined with clinical conditions and other related data for comparative study and statistical analysis. RESULTS: The blood flow spectrum was characterized by diastolic retrograde blood flow spectrum pattern and nail waveform spectrum shape when the patient had clinical brain death. For the parameters of transcranial Doppler, there were significant differences in MCA-Vm and PI between clinical brain death group and normal control group (P < 0.05). For the parameters of echocardiography, there were statistically significant differences in EF, LVMPI, and RVMPI between clinical brain death group and normal control group (P < 0.05). CONCLUSION: Non-invasive dynamic monitoring of cerebral hemodynamics and cardiac function parameters in patients with severe craniocerebral injury can provide a high accuracy and reliability for the preliminary diagnosis of brain death in patients with severe craniocerebral injury. It is helpful for early evaluation of prognosis and provides effective monitoring methods and guidance for clinical treatment. |
format | Online Article Text |
id | pubmed-7702728 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77027282020-12-10 Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging Niu, Ningning Tang, Ying Hao, Xiaoye Wang, Jing Front Neuroinform Neuroscience OBJECTIVES: To investigate the clinical value of non-invasive ultrasound imaging in the evaluation of brain death caused by traumatic brain injury. METHODS: Thirty-four patients with acute severe traumatic brain injury were admitted to hospital within 48 h after injury. All patients were monitored intracranial pressure, transcranial Doppler, echocardiography examination, collection intracranial pressure, MCA-Vs, MCA-Vd, MCA-Vm, EF, LVMPI, RVMPI and other indicators, and combined with clinical conditions and other related data for comparative study and statistical analysis. RESULTS: The blood flow spectrum was characterized by diastolic retrograde blood flow spectrum pattern and nail waveform spectrum shape when the patient had clinical brain death. For the parameters of transcranial Doppler, there were significant differences in MCA-Vm and PI between clinical brain death group and normal control group (P < 0.05). For the parameters of echocardiography, there were statistically significant differences in EF, LVMPI, and RVMPI between clinical brain death group and normal control group (P < 0.05). CONCLUSION: Non-invasive dynamic monitoring of cerebral hemodynamics and cardiac function parameters in patients with severe craniocerebral injury can provide a high accuracy and reliability for the preliminary diagnosis of brain death in patients with severe craniocerebral injury. It is helpful for early evaluation of prognosis and provides effective monitoring methods and guidance for clinical treatment. Frontiers Media S.A. 2020-11-16 /pmc/articles/PMC7702728/ /pubmed/33312121 http://dx.doi.org/10.3389/fninf.2020.607365 Text en Copyright © 2020 Niu, Tang, Hao and Wang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Niu, Ningning Tang, Ying Hao, Xiaoye Wang, Jing Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging |
title | Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging |
title_full | Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging |
title_fullStr | Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging |
title_full_unstemmed | Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging |
title_short | Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging |
title_sort | non-invasive evaluation of brain death caused by traumatic brain injury by ultrasound imaging |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702728/ https://www.ncbi.nlm.nih.gov/pubmed/33312121 http://dx.doi.org/10.3389/fninf.2020.607365 |
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