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Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis

An 80-year-old Japanese woman with diabetes mellitus was admitted with gastrointestinal symptoms and pyrexia. At presentation, liver abscesses and severe hemolytic anemia were noted. Before detailed diagnostic evaluation and adequate treatment, she suddenly died 2.5 hours after admission. The autops...

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Detalles Bibliográficos
Autor principal: Chinen, Katsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703123/
https://www.ncbi.nlm.nih.gov/pubmed/33344302
http://dx.doi.org/10.4322/acr.2020.185
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description An 80-year-old Japanese woman with diabetes mellitus was admitted with gastrointestinal symptoms and pyrexia. At presentation, liver abscesses and severe hemolytic anemia were noted. Before detailed diagnostic evaluation and adequate treatment, she suddenly died 2.5 hours after admission. The autopsy and bacteriological examinations revealed liver abscesses and massive intravascular hemolysis caused by Clostridium perfringens as well as other miscellaneous critical pathological findings, including acute renal tubular necrosis, lung edema, and pulmonary fat embolism. In this article, the detailed autopsy results are described and clinicopathologic characteristics on Clostridium perfringens-related sudden death are discussed with a review of the literature.
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spelling pubmed-77031232020-12-18 Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis Chinen, Katsuya Autops Case Rep Article / Autopsy Case Report An 80-year-old Japanese woman with diabetes mellitus was admitted with gastrointestinal symptoms and pyrexia. At presentation, liver abscesses and severe hemolytic anemia were noted. Before detailed diagnostic evaluation and adequate treatment, she suddenly died 2.5 hours after admission. The autopsy and bacteriological examinations revealed liver abscesses and massive intravascular hemolysis caused by Clostridium perfringens as well as other miscellaneous critical pathological findings, including acute renal tubular necrosis, lung edema, and pulmonary fat embolism. In this article, the detailed autopsy results are described and clinicopathologic characteristics on Clostridium perfringens-related sudden death are discussed with a review of the literature. São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2020-07-30 /pmc/articles/PMC7703123/ /pubmed/33344302 http://dx.doi.org/10.4322/acr.2020.185 Text en Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2020. https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article / Autopsy Case Report
Chinen, Katsuya
Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis
title Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis
title_full Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis
title_fullStr Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis
title_full_unstemmed Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis
title_short Sudden death caused by Clostridium perfringens sepsis presenting as massive intravascular hemolysis
title_sort sudden death caused by clostridium perfringens sepsis presenting as massive intravascular hemolysis
topic Article / Autopsy Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703123/
https://www.ncbi.nlm.nih.gov/pubmed/33344302
http://dx.doi.org/10.4322/acr.2020.185
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