Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer

Background: The CA 19-9 tumor marker is commonly used alongside imaging to trend chemotherapy response in patients with pancreatic ductal adenocarcinoma. Presentation: We describe an unusual clinical case of metastatic pancreatic cancer who achieved a marked decline in CA 19-9 but paradoxically deve...

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Autores principales: King, Daniel A., Pineda, Gino, Jhun, Iny, Fisher, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703254/
https://www.ncbi.nlm.nih.gov/pubmed/33269335
http://dx.doi.org/10.1089/pancan.2020.0015
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author King, Daniel A.
Pineda, Gino
Jhun, Iny
Fisher, George
author_facet King, Daniel A.
Pineda, Gino
Jhun, Iny
Fisher, George
author_sort King, Daniel A.
collection PubMed
description Background: The CA 19-9 tumor marker is commonly used alongside imaging to trend chemotherapy response in patients with pancreatic ductal adenocarcinoma. Presentation: We describe an unusual clinical case of metastatic pancreatic cancer who achieved a marked decline in CA 19-9 but paradoxically developed widespread pulmonary lymphangitic carcinomatosis leading to rapid clinical decline and death. Conclusions: This case highlights the limitations of using the CA 19-9 tumor marker in isolation.
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spelling pubmed-77032542020-12-01 Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer King, Daniel A. Pineda, Gino Jhun, Iny Fisher, George J Pancreat Cancer Case Report Background: The CA 19-9 tumor marker is commonly used alongside imaging to trend chemotherapy response in patients with pancreatic ductal adenocarcinoma. Presentation: We describe an unusual clinical case of metastatic pancreatic cancer who achieved a marked decline in CA 19-9 but paradoxically developed widespread pulmonary lymphangitic carcinomatosis leading to rapid clinical decline and death. Conclusions: This case highlights the limitations of using the CA 19-9 tumor marker in isolation. Mary Ann Liebert, Inc., publishers 2020-11-16 /pmc/articles/PMC7703254/ /pubmed/33269335 http://dx.doi.org/10.1089/pancan.2020.0015 Text en © Daniel A. King et al., 2020; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
King, Daniel A.
Pineda, Gino
Jhun, Iny
Fisher, George
Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer
title Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer
title_full Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer
title_fullStr Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer
title_full_unstemmed Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer
title_short Marked Decrease in CA 19-9 Level Belies Rapidly Progressive Lymphangitic Carcinomatosis in a Case of Metastatic Pancreatic Cancer
title_sort marked decrease in ca 19-9 level belies rapidly progressive lymphangitic carcinomatosis in a case of metastatic pancreatic cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703254/
https://www.ncbi.nlm.nih.gov/pubmed/33269335
http://dx.doi.org/10.1089/pancan.2020.0015
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