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Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes

A mathematical model for the transmission dynamics of Coronavirus diseases (COVID-19) is proposed using a system of nonlinear ordinary differential equations by incorporating self protection behavior changes in the population. The disease free equilibrium point is computed, and both the local and gl...

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Autores principales: Mekonen, Kassahun Getnet, Habtemicheal, Tatek Getachew, Balcha, Shiferaw Feyissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703270/
http://dx.doi.org/10.1016/j.rinam.2020.100134
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author Mekonen, Kassahun Getnet
Habtemicheal, Tatek Getachew
Balcha, Shiferaw Feyissa
author_facet Mekonen, Kassahun Getnet
Habtemicheal, Tatek Getachew
Balcha, Shiferaw Feyissa
author_sort Mekonen, Kassahun Getnet
collection PubMed
description A mathematical model for the transmission dynamics of Coronavirus diseases (COVID-19) is proposed using a system of nonlinear ordinary differential equations by incorporating self protection behavior changes in the population. The disease free equilibrium point is computed, and both the local and global stability analysis was performed. The basic reproduction number ([Formula: see text]) of the model is computed using the method of next generation matrix. The disease free equilibrium point is locally asymptotically and globally stable under certain conditions. Based on the available data, the unknown model parameters are estimated using a combination of least square and Bayesian estimation methods for different countries. The forward sensitivity index is applied to determine and identify the key model parameters for the spread of disease dynamics. The sensitive parameters for the spread of the virus vary from country to country. We found out that the reproduction number depends mostly on the infection rates, the threshold value of the force of infection for a population, the recovery rates, and the virus decay rate in the environment. It illustrates that control of the effective transmission rate (recommended human behavioral change towards self-protective measures) is essential to stop the spreading of the virus. Numerical simulations of the model were performed to supplement and verify the effectiveness of the analytical findings.
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spelling pubmed-77032702020-12-01 Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes Mekonen, Kassahun Getnet Habtemicheal, Tatek Getachew Balcha, Shiferaw Feyissa Results in Applied Mathematics Article A mathematical model for the transmission dynamics of Coronavirus diseases (COVID-19) is proposed using a system of nonlinear ordinary differential equations by incorporating self protection behavior changes in the population. The disease free equilibrium point is computed, and both the local and global stability analysis was performed. The basic reproduction number ([Formula: see text]) of the model is computed using the method of next generation matrix. The disease free equilibrium point is locally asymptotically and globally stable under certain conditions. Based on the available data, the unknown model parameters are estimated using a combination of least square and Bayesian estimation methods for different countries. The forward sensitivity index is applied to determine and identify the key model parameters for the spread of disease dynamics. The sensitive parameters for the spread of the virus vary from country to country. We found out that the reproduction number depends mostly on the infection rates, the threshold value of the force of infection for a population, the recovery rates, and the virus decay rate in the environment. It illustrates that control of the effective transmission rate (recommended human behavioral change towards self-protective measures) is essential to stop the spreading of the virus. Numerical simulations of the model were performed to supplement and verify the effectiveness of the analytical findings. The Author(s). Published by Elsevier B.V. 2021-02 2020-11-30 /pmc/articles/PMC7703270/ http://dx.doi.org/10.1016/j.rinam.2020.100134 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Mekonen, Kassahun Getnet
Habtemicheal, Tatek Getachew
Balcha, Shiferaw Feyissa
Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes
title Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes
title_full Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes
title_fullStr Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes
title_full_unstemmed Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes
title_short Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes
title_sort modeling the effect of contaminated objects for the transmission dynamics of covid-19 pandemic with self protection behavior changes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703270/
http://dx.doi.org/10.1016/j.rinam.2020.100134
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