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RNA-Seq Analysis of Colorectal Tumor-Infiltrating Myeloid-Derived Suppressor Cell Subsets Revealed Gene Signatures of Poor Prognosis

Elevated levels of myeloid-derived suppressor cells (MDSCs), including polymorphonuclear MDSCs (PMN-MDSCs) and immature MDSCs (I-MDSCs), are usually associated with disease progression in cancer patients, including colorectal cancer (CRC). However, biological mechanisms and molecular pathways regula...

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Detalles Bibliográficos
Autores principales: Saleh, Reem, Sasidharan Nair, Varun, Al-Dhaheri, Mahmood, Khawar, Mahwish, Abu Nada, Mohamed, Alajez, Nehad M., Elkord, Eyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703275/
https://www.ncbi.nlm.nih.gov/pubmed/33312958
http://dx.doi.org/10.3389/fonc.2020.604906