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Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location

Prostate cancer is one of the commonest cancers among men contributing significantly to the overall cancer burden globally. Most patients present with lower urinary tract symptoms. Metastasis to supraclavicular lymph nodes is unusual presentation, which has been rarely reported particularly as the p...

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Autores principales: Mbwambo, Orgeness J, Mremi, Alex, Mbwambo, Jasper S, Bright, Frank, Mteta, Alfred K, Ngowi, Bartholomeo N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703372/
https://www.ncbi.nlm.nih.gov/pubmed/33294165
http://dx.doi.org/10.1093/jscr/rjaa476
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author Mbwambo, Orgeness J
Mremi, Alex
Mbwambo, Jasper S
Bright, Frank
Mteta, Alfred K
Ngowi, Bartholomeo N
author_facet Mbwambo, Orgeness J
Mremi, Alex
Mbwambo, Jasper S
Bright, Frank
Mteta, Alfred K
Ngowi, Bartholomeo N
author_sort Mbwambo, Orgeness J
collection PubMed
description Prostate cancer is one of the commonest cancers among men contributing significantly to the overall cancer burden globally. Most patients present with lower urinary tract symptoms. Metastasis to supraclavicular lymph nodes is unusual presentation, which has been rarely reported particularly as the primary presentation. We report two rare cases of advanced prostatic adenocarcinoma presenting with firm, non-tender lump in the left supraclavicular region between the two heads of the sternocleidomastoid muscle, (that is Virchow’s node) as initial primary symptom. Examination of the patients revealed an elevated prostatic-specific antigen (PSA) of > 100 ng/ml levels, and the diagnosis was confirmed by histological evaluation and immunostaining with PSA of the supraclavicular lymph nodes and prostate biopsies. This case series emphasizes the importance of considering prostate cancer in the differential diagnosis of male patients with supraclavicular lymphadenopathy.
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spelling pubmed-77033722020-12-07 Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location Mbwambo, Orgeness J Mremi, Alex Mbwambo, Jasper S Bright, Frank Mteta, Alfred K Ngowi, Bartholomeo N J Surg Case Rep Case Series Prostate cancer is one of the commonest cancers among men contributing significantly to the overall cancer burden globally. Most patients present with lower urinary tract symptoms. Metastasis to supraclavicular lymph nodes is unusual presentation, which has been rarely reported particularly as the primary presentation. We report two rare cases of advanced prostatic adenocarcinoma presenting with firm, non-tender lump in the left supraclavicular region between the two heads of the sternocleidomastoid muscle, (that is Virchow’s node) as initial primary symptom. Examination of the patients revealed an elevated prostatic-specific antigen (PSA) of > 100 ng/ml levels, and the diagnosis was confirmed by histological evaluation and immunostaining with PSA of the supraclavicular lymph nodes and prostate biopsies. This case series emphasizes the importance of considering prostate cancer in the differential diagnosis of male patients with supraclavicular lymphadenopathy. Oxford University Press 2020-11-30 /pmc/articles/PMC7703372/ /pubmed/33294165 http://dx.doi.org/10.1093/jscr/rjaa476 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Series
Mbwambo, Orgeness J
Mremi, Alex
Mbwambo, Jasper S
Bright, Frank
Mteta, Alfred K
Ngowi, Bartholomeo N
Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
title Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
title_full Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
title_fullStr Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
title_full_unstemmed Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
title_short Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
title_sort virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703372/
https://www.ncbi.nlm.nih.gov/pubmed/33294165
http://dx.doi.org/10.1093/jscr/rjaa476
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