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Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location
Prostate cancer is one of the commonest cancers among men contributing significantly to the overall cancer burden globally. Most patients present with lower urinary tract symptoms. Metastasis to supraclavicular lymph nodes is unusual presentation, which has been rarely reported particularly as the p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703372/ https://www.ncbi.nlm.nih.gov/pubmed/33294165 http://dx.doi.org/10.1093/jscr/rjaa476 |
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author | Mbwambo, Orgeness J Mremi, Alex Mbwambo, Jasper S Bright, Frank Mteta, Alfred K Ngowi, Bartholomeo N |
author_facet | Mbwambo, Orgeness J Mremi, Alex Mbwambo, Jasper S Bright, Frank Mteta, Alfred K Ngowi, Bartholomeo N |
author_sort | Mbwambo, Orgeness J |
collection | PubMed |
description | Prostate cancer is one of the commonest cancers among men contributing significantly to the overall cancer burden globally. Most patients present with lower urinary tract symptoms. Metastasis to supraclavicular lymph nodes is unusual presentation, which has been rarely reported particularly as the primary presentation. We report two rare cases of advanced prostatic adenocarcinoma presenting with firm, non-tender lump in the left supraclavicular region between the two heads of the sternocleidomastoid muscle, (that is Virchow’s node) as initial primary symptom. Examination of the patients revealed an elevated prostatic-specific antigen (PSA) of > 100 ng/ml levels, and the diagnosis was confirmed by histological evaluation and immunostaining with PSA of the supraclavicular lymph nodes and prostate biopsies. This case series emphasizes the importance of considering prostate cancer in the differential diagnosis of male patients with supraclavicular lymphadenopathy. |
format | Online Article Text |
id | pubmed-7703372 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-77033722020-12-07 Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location Mbwambo, Orgeness J Mremi, Alex Mbwambo, Jasper S Bright, Frank Mteta, Alfred K Ngowi, Bartholomeo N J Surg Case Rep Case Series Prostate cancer is one of the commonest cancers among men contributing significantly to the overall cancer burden globally. Most patients present with lower urinary tract symptoms. Metastasis to supraclavicular lymph nodes is unusual presentation, which has been rarely reported particularly as the primary presentation. We report two rare cases of advanced prostatic adenocarcinoma presenting with firm, non-tender lump in the left supraclavicular region between the two heads of the sternocleidomastoid muscle, (that is Virchow’s node) as initial primary symptom. Examination of the patients revealed an elevated prostatic-specific antigen (PSA) of > 100 ng/ml levels, and the diagnosis was confirmed by histological evaluation and immunostaining with PSA of the supraclavicular lymph nodes and prostate biopsies. This case series emphasizes the importance of considering prostate cancer in the differential diagnosis of male patients with supraclavicular lymphadenopathy. Oxford University Press 2020-11-30 /pmc/articles/PMC7703372/ /pubmed/33294165 http://dx.doi.org/10.1093/jscr/rjaa476 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Series Mbwambo, Orgeness J Mremi, Alex Mbwambo, Jasper S Bright, Frank Mteta, Alfred K Ngowi, Bartholomeo N Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location |
title | Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location |
title_full | Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location |
title_fullStr | Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location |
title_full_unstemmed | Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location |
title_short | Virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location |
title_sort | virchow’s node as the initial presentation of metastatic prostate cancer: a case series of a common cancer in uncommon location |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703372/ https://www.ncbi.nlm.nih.gov/pubmed/33294165 http://dx.doi.org/10.1093/jscr/rjaa476 |
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