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A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction

Patient: Male, 63-year-old Final Diagnosis: Eccrine porocarcinoma Symptoms: Pain Medication: — Clinical Procedure: Resection of hand cancer Specialty: Surgery OBJECTIVE: Rare co-existance of disease or pathology BACKGROUND: Eccrine porocarcinoma (EPC) was first described in 1963 as an epidermotropic...

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Autores principales: Chow, Kevin L., Peters, Xane, Mashbari, Hassan, Shokouh-Amiri, Mohammad, Benjamin, Martin, Warso, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703490/
https://www.ncbi.nlm.nih.gov/pubmed/33242313
http://dx.doi.org/10.12659/AJCR.925231
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author Chow, Kevin L.
Peters, Xane
Mashbari, Hassan
Shokouh-Amiri, Mohammad
Benjamin, Martin
Warso, Michael
author_facet Chow, Kevin L.
Peters, Xane
Mashbari, Hassan
Shokouh-Amiri, Mohammad
Benjamin, Martin
Warso, Michael
author_sort Chow, Kevin L.
collection PubMed
description Patient: Male, 63-year-old Final Diagnosis: Eccrine porocarcinoma Symptoms: Pain Medication: — Clinical Procedure: Resection of hand cancer Specialty: Surgery OBJECTIVE: Rare co-existance of disease or pathology BACKGROUND: Eccrine porocarcinoma (EPC) was first described in 1963 as an epidermotropic eccrine carcinoma. Fifty years later, its etiology remains poorly understood. The infrequent nature of this disease merits further inquiry into its etiology, presentation, and standards of management. Furthermore, the propensity for metastasis, which may be as high as 31% on presentation, increases the importance of investigating this rare disease. CASE REPORT: The patient was a 63-year-old mechanic who presented with the lesion as a chronic wound following a chemical exposure. The lesion involved the ulnar aspect of his right palm and had concern for extension to the underlying tendons. He underwent a wide excision extending from the wrist to the proximal interphalangeal joint, preserving the ulnar neurovascular bundle. The hand was reconstructed with an anterolateral thigh fascia perforator flap and a skin graft. He had an excellent functional and cosmetic recovery. Unfortunately, he developed metastases to the lymph nodes, necessitating an axillary lymphadenectomy followed by adjuvant chemoradiation using concurrent cisplatin and docetaxel with radiation for 6 weeks. Follow-up at 18 months found no recurrence. CONCLUSIONS: Cases of EPC presenting in the fingers have been managed with amputation of the involved phalanges; however, in addition to obtaining complete excision with negative margins, surgeons who deal with tumors of the hand must also consider the goals of limb preservation, functional preservation, and functional reconstruction. Options for reconstruction following excision include primary closure, dermal regeneration templates, skin grafts, flaps, and free-tissue transfer, depending on what tissue types are needed.
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spelling pubmed-77034902020-12-04 A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction Chow, Kevin L. Peters, Xane Mashbari, Hassan Shokouh-Amiri, Mohammad Benjamin, Martin Warso, Michael Am J Case Rep Articles Patient: Male, 63-year-old Final Diagnosis: Eccrine porocarcinoma Symptoms: Pain Medication: — Clinical Procedure: Resection of hand cancer Specialty: Surgery OBJECTIVE: Rare co-existance of disease or pathology BACKGROUND: Eccrine porocarcinoma (EPC) was first described in 1963 as an epidermotropic eccrine carcinoma. Fifty years later, its etiology remains poorly understood. The infrequent nature of this disease merits further inquiry into its etiology, presentation, and standards of management. Furthermore, the propensity for metastasis, which may be as high as 31% on presentation, increases the importance of investigating this rare disease. CASE REPORT: The patient was a 63-year-old mechanic who presented with the lesion as a chronic wound following a chemical exposure. The lesion involved the ulnar aspect of his right palm and had concern for extension to the underlying tendons. He underwent a wide excision extending from the wrist to the proximal interphalangeal joint, preserving the ulnar neurovascular bundle. The hand was reconstructed with an anterolateral thigh fascia perforator flap and a skin graft. He had an excellent functional and cosmetic recovery. Unfortunately, he developed metastases to the lymph nodes, necessitating an axillary lymphadenectomy followed by adjuvant chemoradiation using concurrent cisplatin and docetaxel with radiation for 6 weeks. Follow-up at 18 months found no recurrence. CONCLUSIONS: Cases of EPC presenting in the fingers have been managed with amputation of the involved phalanges; however, in addition to obtaining complete excision with negative margins, surgeons who deal with tumors of the hand must also consider the goals of limb preservation, functional preservation, and functional reconstruction. Options for reconstruction following excision include primary closure, dermal regeneration templates, skin grafts, flaps, and free-tissue transfer, depending on what tissue types are needed. International Scientific Literature, Inc. 2020-11-26 /pmc/articles/PMC7703490/ /pubmed/33242313 http://dx.doi.org/10.12659/AJCR.925231 Text en © Am J Case Rep, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Chow, Kevin L.
Peters, Xane
Mashbari, Hassan
Shokouh-Amiri, Mohammad
Benjamin, Martin
Warso, Michael
A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
title A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
title_full A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
title_fullStr A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
title_full_unstemmed A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
title_short A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
title_sort case report of malignant eccrine porocarcinoma involving the palm requiring surgical excision and free flap reconstruction
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703490/
https://www.ncbi.nlm.nih.gov/pubmed/33242313
http://dx.doi.org/10.12659/AJCR.925231
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