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A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
Patient: Male, 63-year-old Final Diagnosis: Eccrine porocarcinoma Symptoms: Pain Medication: — Clinical Procedure: Resection of hand cancer Specialty: Surgery OBJECTIVE: Rare co-existance of disease or pathology BACKGROUND: Eccrine porocarcinoma (EPC) was first described in 1963 as an epidermotropic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703490/ https://www.ncbi.nlm.nih.gov/pubmed/33242313 http://dx.doi.org/10.12659/AJCR.925231 |
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author | Chow, Kevin L. Peters, Xane Mashbari, Hassan Shokouh-Amiri, Mohammad Benjamin, Martin Warso, Michael |
author_facet | Chow, Kevin L. Peters, Xane Mashbari, Hassan Shokouh-Amiri, Mohammad Benjamin, Martin Warso, Michael |
author_sort | Chow, Kevin L. |
collection | PubMed |
description | Patient: Male, 63-year-old Final Diagnosis: Eccrine porocarcinoma Symptoms: Pain Medication: — Clinical Procedure: Resection of hand cancer Specialty: Surgery OBJECTIVE: Rare co-existance of disease or pathology BACKGROUND: Eccrine porocarcinoma (EPC) was first described in 1963 as an epidermotropic eccrine carcinoma. Fifty years later, its etiology remains poorly understood. The infrequent nature of this disease merits further inquiry into its etiology, presentation, and standards of management. Furthermore, the propensity for metastasis, which may be as high as 31% on presentation, increases the importance of investigating this rare disease. CASE REPORT: The patient was a 63-year-old mechanic who presented with the lesion as a chronic wound following a chemical exposure. The lesion involved the ulnar aspect of his right palm and had concern for extension to the underlying tendons. He underwent a wide excision extending from the wrist to the proximal interphalangeal joint, preserving the ulnar neurovascular bundle. The hand was reconstructed with an anterolateral thigh fascia perforator flap and a skin graft. He had an excellent functional and cosmetic recovery. Unfortunately, he developed metastases to the lymph nodes, necessitating an axillary lymphadenectomy followed by adjuvant chemoradiation using concurrent cisplatin and docetaxel with radiation for 6 weeks. Follow-up at 18 months found no recurrence. CONCLUSIONS: Cases of EPC presenting in the fingers have been managed with amputation of the involved phalanges; however, in addition to obtaining complete excision with negative margins, surgeons who deal with tumors of the hand must also consider the goals of limb preservation, functional preservation, and functional reconstruction. Options for reconstruction following excision include primary closure, dermal regeneration templates, skin grafts, flaps, and free-tissue transfer, depending on what tissue types are needed. |
format | Online Article Text |
id | pubmed-7703490 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77034902020-12-04 A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction Chow, Kevin L. Peters, Xane Mashbari, Hassan Shokouh-Amiri, Mohammad Benjamin, Martin Warso, Michael Am J Case Rep Articles Patient: Male, 63-year-old Final Diagnosis: Eccrine porocarcinoma Symptoms: Pain Medication: — Clinical Procedure: Resection of hand cancer Specialty: Surgery OBJECTIVE: Rare co-existance of disease or pathology BACKGROUND: Eccrine porocarcinoma (EPC) was first described in 1963 as an epidermotropic eccrine carcinoma. Fifty years later, its etiology remains poorly understood. The infrequent nature of this disease merits further inquiry into its etiology, presentation, and standards of management. Furthermore, the propensity for metastasis, which may be as high as 31% on presentation, increases the importance of investigating this rare disease. CASE REPORT: The patient was a 63-year-old mechanic who presented with the lesion as a chronic wound following a chemical exposure. The lesion involved the ulnar aspect of his right palm and had concern for extension to the underlying tendons. He underwent a wide excision extending from the wrist to the proximal interphalangeal joint, preserving the ulnar neurovascular bundle. The hand was reconstructed with an anterolateral thigh fascia perforator flap and a skin graft. He had an excellent functional and cosmetic recovery. Unfortunately, he developed metastases to the lymph nodes, necessitating an axillary lymphadenectomy followed by adjuvant chemoradiation using concurrent cisplatin and docetaxel with radiation for 6 weeks. Follow-up at 18 months found no recurrence. CONCLUSIONS: Cases of EPC presenting in the fingers have been managed with amputation of the involved phalanges; however, in addition to obtaining complete excision with negative margins, surgeons who deal with tumors of the hand must also consider the goals of limb preservation, functional preservation, and functional reconstruction. Options for reconstruction following excision include primary closure, dermal regeneration templates, skin grafts, flaps, and free-tissue transfer, depending on what tissue types are needed. International Scientific Literature, Inc. 2020-11-26 /pmc/articles/PMC7703490/ /pubmed/33242313 http://dx.doi.org/10.12659/AJCR.925231 Text en © Am J Case Rep, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) |
spellingShingle | Articles Chow, Kevin L. Peters, Xane Mashbari, Hassan Shokouh-Amiri, Mohammad Benjamin, Martin Warso, Michael A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction |
title | A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction |
title_full | A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction |
title_fullStr | A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction |
title_full_unstemmed | A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction |
title_short | A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction |
title_sort | case report of malignant eccrine porocarcinoma involving the palm requiring surgical excision and free flap reconstruction |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703490/ https://www.ncbi.nlm.nih.gov/pubmed/33242313 http://dx.doi.org/10.12659/AJCR.925231 |
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