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Persistent hiccup: A rare presentation of COVID-19

BACKGROUND: Hiccups are involuntary diaphragmatic muscle contractions with early glottis closure terminating inspiration. They are classified into two types: acute (<48 hours) and persistent (>48 hours). COVID-19 is the defining health crisis of our generation. Although there are common sympto...

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Autores principales: Bakheet, Nader, Fouad, Rabab, Kassem, Abdel Meguid, Hussin, Wessam, El-Shazly, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Respiratory Society. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703547/
https://www.ncbi.nlm.nih.gov/pubmed/33309013
http://dx.doi.org/10.1016/j.resinv.2020.11.003
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author Bakheet, Nader
Fouad, Rabab
Kassem, Abdel Meguid
Hussin, Wessam
El-Shazly, Mostafa
author_facet Bakheet, Nader
Fouad, Rabab
Kassem, Abdel Meguid
Hussin, Wessam
El-Shazly, Mostafa
author_sort Bakheet, Nader
collection PubMed
description BACKGROUND: Hiccups are involuntary diaphragmatic muscle contractions with early glottis closure terminating inspiration. They are classified into two types: acute (<48 hours) and persistent (>48 hours). COVID-19 is the defining health crisis of our generation. Although there are common symptoms of the disease (e.g. fever, cough), several atypical presentations have appeared as the pandemic has evolved. Here, we present a patient with COVID-19 presenting with fever, sore throat, and persistent hiccups. METHODS AND RESULTS: A 48-year-old man presented to the hospital with a seven-day history of persistent hiccups, fever, and sore throat. Physical examination was unremarkable and abdominal ultrasound showed gaseous abdominal distension. Laboratory values were remarkable for elevated C-reactive protein, ferritin, and lactate dehydrogenase levels. Computed tomography of the chest showed bilateral subpleural areas of ground-glass attenuation and crazy-paving pattern. A COVID-19 test was positive, and hydroxychloroquine, oseltamivir, baclofen, and symptomatic treatment were initiated. The hiccups improved, and the patient was discharged home after ten days. CONCLUSION: Physicians should maintain a high level of suspicion and be aware of atypical presentations of COVID-19.
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spelling pubmed-77035472020-12-01 Persistent hiccup: A rare presentation of COVID-19 Bakheet, Nader Fouad, Rabab Kassem, Abdel Meguid Hussin, Wessam El-Shazly, Mostafa Respir Investig Case Report BACKGROUND: Hiccups are involuntary diaphragmatic muscle contractions with early glottis closure terminating inspiration. They are classified into two types: acute (<48 hours) and persistent (>48 hours). COVID-19 is the defining health crisis of our generation. Although there are common symptoms of the disease (e.g. fever, cough), several atypical presentations have appeared as the pandemic has evolved. Here, we present a patient with COVID-19 presenting with fever, sore throat, and persistent hiccups. METHODS AND RESULTS: A 48-year-old man presented to the hospital with a seven-day history of persistent hiccups, fever, and sore throat. Physical examination was unremarkable and abdominal ultrasound showed gaseous abdominal distension. Laboratory values were remarkable for elevated C-reactive protein, ferritin, and lactate dehydrogenase levels. Computed tomography of the chest showed bilateral subpleural areas of ground-glass attenuation and crazy-paving pattern. A COVID-19 test was positive, and hydroxychloroquine, oseltamivir, baclofen, and symptomatic treatment were initiated. The hiccups improved, and the patient was discharged home after ten days. CONCLUSION: Physicians should maintain a high level of suspicion and be aware of atypical presentations of COVID-19. The Japanese Respiratory Society. Published by Elsevier B.V. 2021-03 2020-11-30 /pmc/articles/PMC7703547/ /pubmed/33309013 http://dx.doi.org/10.1016/j.resinv.2020.11.003 Text en © 2020 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Bakheet, Nader
Fouad, Rabab
Kassem, Abdel Meguid
Hussin, Wessam
El-Shazly, Mostafa
Persistent hiccup: A rare presentation of COVID-19
title Persistent hiccup: A rare presentation of COVID-19
title_full Persistent hiccup: A rare presentation of COVID-19
title_fullStr Persistent hiccup: A rare presentation of COVID-19
title_full_unstemmed Persistent hiccup: A rare presentation of COVID-19
title_short Persistent hiccup: A rare presentation of COVID-19
title_sort persistent hiccup: a rare presentation of covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703547/
https://www.ncbi.nlm.nih.gov/pubmed/33309013
http://dx.doi.org/10.1016/j.resinv.2020.11.003
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