Somatic selection distinguishes oncogenes and tumor suppressor genes

MOTIVATION: Functions of cancer driver genes vary substantially across tissues and organs. Distinguishing passenger genes, oncogenes (OGs) and tumor-suppressor genes (TSGs) for each cancer type is critical for understanding tumor biology and identifying clinically actionable targets. Although many c...

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Detalles Bibliográficos
Autores principales: Chandrashekar, Pramod, Ahmadinejad, Navid, Wang, Junwen, Sekulic, Aleksandar, Egan, Jan B, Asmann, Yan W, Kumar, Sudhir, Maley, Carlo, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703750/
https://www.ncbi.nlm.nih.gov/pubmed/32176769
http://dx.doi.org/10.1093/bioinformatics/btz851

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