Cocaine vaccine dAd5GNE protects against moderate daily and high-dose “binge” cocaine use

The cocaine vaccine dAd5GNE is comprised of a disrupted serotype 5 adenovirus gene therapy vector covalently conjugated to the cocaine analog GNE. The vaccine evokes a high titer of circulating anti-cocaine antibodies that prevent cocaine from reaching its cognate receptors in the central nervous sy...

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Detalles Bibliográficos
Autores principales: Havlicek, David F., Rosenberg, Jonathan B., De, Bishnu P., Hicks, Martin J., Sondhi, Dolan, Kaminsky, Stephen M., Crystal, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703925/
https://www.ncbi.nlm.nih.gov/pubmed/33253224
http://dx.doi.org/10.1371/journal.pone.0239780

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