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Clinical Perspective of FDA Approved Drugs With P-Glycoprotein Inhibition Activities for Potential Cancer Therapeutics
P-glycoprotein (also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) plays a crucial role in determining response against medications, including cancer therapeutics. It is now well established that p-glycoprotein acts as an ATP dependent pump that...
Autores principales: | Lai, Jiun-I, Tseng, Yu-Jhen, Chen, Ming-Huang, Huang, Chi-Ying F., Chang, Peter Mu-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704056/ https://www.ncbi.nlm.nih.gov/pubmed/33312947 http://dx.doi.org/10.3389/fonc.2020.561936 |
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