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Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11

Plasmodium sporozoites express circumsporozoite protein (CSP) on their surface, an essential protein that contains central repeating motifs. Antibodies targeting this region can neutralize infection, and the partial efficacy of RTS,S/AS01 – the leading malaria vaccine against P. falciparum (Pf) – ha...

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Detalles Bibliográficos
Autores principales: Kucharska, Iga, Thai, Elaine, Srivastava, Ananya, Rubinstein, John L, Pomès, Régis, Julien, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704109/
https://www.ncbi.nlm.nih.gov/pubmed/33253113
http://dx.doi.org/10.7554/eLife.59018