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Neonatal microglia-organized scar-free spinal cord repair

It is thought that spinal cord injury triggers scar formation with little axon regeneration in mammals(1–4). Here we report that in neonatal mice, a crush injury to the spinal cord leads to a scar-free healing that permits the growth of long projecting axons through the lesion. Depletion of microgli...

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Detalles Bibliográficos
Autores principales: Li, Yi, He, Xuelian, Kawaguchi, Riki, Zhang, Yu, Wang, Qing, Monavarfeshani, Aboozar, Yang, Zhiyun, Chen, Bo, Shi, Zhongju, Meng, Huyan, Zhou, Songlin, Zhu, Junjie, Jacobi, Anne, Swarup, Vivek, Popovich, Phillip G., Geschwind, Daniel H, He, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704837/
https://www.ncbi.nlm.nih.gov/pubmed/33029008
http://dx.doi.org/10.1038/s41586-020-2795-6