Cargando…
Neonatal microglia-organized scar-free spinal cord repair
It is thought that spinal cord injury triggers scar formation with little axon regeneration in mammals(1–4). Here we report that in neonatal mice, a crush injury to the spinal cord leads to a scar-free healing that permits the growth of long projecting axons through the lesion. Depletion of microgli...
Autores principales: | Li, Yi, He, Xuelian, Kawaguchi, Riki, Zhang, Yu, Wang, Qing, Monavarfeshani, Aboozar, Yang, Zhiyun, Chen, Bo, Shi, Zhongju, Meng, Huyan, Zhou, Songlin, Zhu, Junjie, Jacobi, Anne, Swarup, Vivek, Popovich, Phillip G., Geschwind, Daniel H, He, Zhigang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704837/ https://www.ncbi.nlm.nih.gov/pubmed/33029008 http://dx.doi.org/10.1038/s41586-020-2795-6 |
Ejemplares similares
-
Microglia coordinate cellular interactions during spinal cord repair in mice
por: Brennan, Faith H., et al.
Publicado: (2022) -
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury
por: Bellver-Landete, Victor, et al.
Publicado: (2019) -
Retinal-input-induced epigenetic dynamics in the developing mouse dorsal lateral geniculate nucleus
por: He, Jianlin, et al.
Publicado: (2019) -
Deciphering glial scar after spinal cord injury
por: Zhang, Yu, et al.
Publicado: (2021) -
F-spondin Is Essential for Maintaining Circadian Rhythms
por: Carrillo, Gabriela L., et al.
Publicado: (2018)