Pregabalin-associated stuttering and frequent blepharospasm: case report and review.

Herpes zoster is an acute, painful, herpes skin disease caused by varicella-zoster virus, which may cause viral meningitis. Pregabalin has been shown to be efficacious in the treatment of pain in patients with herpes zoster. However, it has the side effects of neurotoxicity. We describe a 68-year-ol...

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Autores principales: Ge, Lingzhi, Li, Ang, Wang, Ni, Li, Ping, Xin, Hongyan, Li, Wenfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704871/
https://www.ncbi.nlm.nih.gov/pubmed/32632575
http://dx.doi.org/10.1007/s40199-020-00354-9
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author Ge, Lingzhi
Li, Ang
Wang, Ni
Li, Ping
Xin, Hongyan
Li, Wenfei
author_facet Ge, Lingzhi
Li, Ang
Wang, Ni
Li, Ping
Xin, Hongyan
Li, Wenfei
author_sort Ge, Lingzhi
collection PubMed
description Herpes zoster is an acute, painful, herpes skin disease caused by varicella-zoster virus, which may cause viral meningitis. Pregabalin has been shown to be efficacious in the treatment of pain in patients with herpes zoster. However, it has the side effects of neurotoxicity. We describe a 68-year-old female patient with herpes zoster, and she was treated with pregabalin. The patient presented with stuttering and frequent blepharospasm after 3 days of pregabalin treatment. Pregabalin was discontinued, the symptoms of stuttering and frequent blepharospasm completely resolved without any special treatment after one week. In this case, the etiology of stuttering and frequent blepharospasm may be related to pregabalin. Clinicians should be alert to the rare symptoms associated with the use of pregabalin. [Figure: see text]
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spelling pubmed-77048712020-12-03 Pregabalin-associated stuttering and frequent blepharospasm: case report and review. Ge, Lingzhi Li, Ang Wang, Ni Li, Ping Xin, Hongyan Li, Wenfei Daru Case Report Herpes zoster is an acute, painful, herpes skin disease caused by varicella-zoster virus, which may cause viral meningitis. Pregabalin has been shown to be efficacious in the treatment of pain in patients with herpes zoster. However, it has the side effects of neurotoxicity. We describe a 68-year-old female patient with herpes zoster, and she was treated with pregabalin. The patient presented with stuttering and frequent blepharospasm after 3 days of pregabalin treatment. Pregabalin was discontinued, the symptoms of stuttering and frequent blepharospasm completely resolved without any special treatment after one week. In this case, the etiology of stuttering and frequent blepharospasm may be related to pregabalin. Clinicians should be alert to the rare symptoms associated with the use of pregabalin. [Figure: see text] Springer International Publishing 2020-07-06 /pmc/articles/PMC7704871/ /pubmed/32632575 http://dx.doi.org/10.1007/s40199-020-00354-9 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Case Report
Ge, Lingzhi
Li, Ang
Wang, Ni
Li, Ping
Xin, Hongyan
Li, Wenfei
Pregabalin-associated stuttering and frequent blepharospasm: case report and review.
title Pregabalin-associated stuttering and frequent blepharospasm: case report and review.
title_full Pregabalin-associated stuttering and frequent blepharospasm: case report and review.
title_fullStr Pregabalin-associated stuttering and frequent blepharospasm: case report and review.
title_full_unstemmed Pregabalin-associated stuttering and frequent blepharospasm: case report and review.
title_short Pregabalin-associated stuttering and frequent blepharospasm: case report and review.
title_sort pregabalin-associated stuttering and frequent blepharospasm: case report and review.
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704871/
https://www.ncbi.nlm.nih.gov/pubmed/32632575
http://dx.doi.org/10.1007/s40199-020-00354-9
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