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Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy

Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment surgery failure. Despite significant advances in vitreoretinal surgery, it still remains without an effective prophylactic or therapeutic medical treatment. After ocular injury or retinal detachment, misplaced retinal c...

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Detalles Bibliográficos
Autores principales: Delgado-Tirado, Santiago, Amarnani, Dhanesh, Zhao, Guannan, Rossin, Elizabeth J., Eliott, Dean, Miller, John B., Greene, Whitney A., Ramos, Leslie, Arevalo-Alquichire, Said, Leyton-Cifuentes, David, Gonzalez-Buendia, Lucia, Isaacs-Bernal, Daniela, Whitmore, Hannah A. B., Chmielewska, Natalia, Duffy, Brandon V., Kim, Eric, Wang, Heuy-Ching, Ruiz-Moreno, Jose M., Kim, Leo A., Arboleda-Velasquez, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705016/
https://www.ncbi.nlm.nih.gov/pubmed/33257736
http://dx.doi.org/10.1038/s41598-020-77254-0