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Re-evaluation of Diadenosine Tetraphosphate (Ap(4)A) From a Stress Metabolite to Bona Fide Secondary Messenger

Cellular homeostasis requires adaption to environmental stress. In response to various environmental and genotoxic stresses, all cells produce dinucleoside polyphosphates (Np(n)Ns), the best studied of which is diadenosine tetraphosphate (Ap(4)A). Despite intensive investigation, the precise biologi...

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Detalles Bibliográficos
Autores principales: Ferguson, Freya, McLennan, Alexander G., Urbaniak, Michael D., Jones, Nigel J., Copeland, Nikki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705103/
https://www.ncbi.nlm.nih.gov/pubmed/33282915
http://dx.doi.org/10.3389/fmolb.2020.606807