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Sphingolipids and Inositol Phosphates Regulate the Tau Protein Phosphorylation Status in Humanized Yeast
Hyperphosphorylation of protein tau is a hallmark of Alzheimer’s disease (AD). Changes in energy and lipid metabolism have been correlated with the late onset of this neurological disorder. However, it is uncertain if metabolic dysregulation is a consequence of AD or one of the initiating factors of...
Autores principales: | Randez-Gil, Francisca, Bojunga, Lino, Estruch, Francisco, Winderickx, Joris, Del Poeta, Maurizio, Prieto, Jose A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705114/ https://www.ncbi.nlm.nih.gov/pubmed/33282871 http://dx.doi.org/10.3389/fcell.2020.592159 |
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