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Apremilast Regulates the Teff/Treg Balance to Ameliorate Uveitis via PI3K/AKT/FoxO1 Signaling Pathway
Autoimmune uveitis (AU), being one of the sight-threatening ocular inflammatory disorders, has been widely regarded by ophthalmologists and immunologists as a great challenge. Apremilast, a phosphodiesterase-4 inhibitor (PDE4i), which was approved by the U.S. Food and Drug Administration (FDA) for t...
Autores principales: | Chen, Yuxi, Li, Zhuang, Li, He, Su, Wenru, Xie, Yanyan, Pan, Yuan, Chen, Xiaoqing, Liang, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705241/ https://www.ncbi.nlm.nih.gov/pubmed/33281814 http://dx.doi.org/10.3389/fimmu.2020.581673 |
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