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Identification of Potential Key Agents for Targeting RNA-Dependent RNA Polymerase of SARS-CoV-2 by Integrated Analysis and Virtual Drug Screening

BACKGROUND: RNA-dependent RNA polymerase (RdRp) is the key enzyme responsible for the SARS-CoV-2 replication process and catalyzes the synthesis of complementary minus strand RNA and genomic plus strand RNA, often recognized as good targets for antiviral drugs. MATERIALS AND METHODS: A systematic sc...

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Detalles Bibliográficos
Autores principales:	Ao, Shuang, Han, Dan, Sun, Lei, Wu, Yanhong, Liu, Shuang, Huang, Yaojiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705243/ https://www.ncbi.nlm.nih.gov/pubmed/33281876 http://dx.doi.org/10.3389/fgene.2020.581668

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