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Participation of Endosomes in Toll-Like Receptor 3 Transportation Pathway in Murine Astrocytes

TLR3 provides immediate type I IFN response following entry of stimulatory PAMPs into the CNS, as it is in HSV infection. The receptor plays a vital role in astrocytes, contributing to rapid infection sensing and suppression of viral replication, precluding the spread of virus beyond neurons. The ro...

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Detalles Bibliográficos
Autores principales: Mielcarska, Matylda B., Gregorczyk-Zboroch, Karolina P., Szulc-Dąbrowska, Lidia, Bossowska-Nowicka, Magdalena, Wyżewski, Zbigniew, Cymerys, Joanna, Chodkowski, Marcin, Kiełbik, Paula, Godlewski, Michał M., Gieryńska, Małgorzata, Toka, Felix N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705377/
https://www.ncbi.nlm.nih.gov/pubmed/33281554
http://dx.doi.org/10.3389/fncel.2020.544612