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Participation of Endosomes in Toll-Like Receptor 3 Transportation Pathway in Murine Astrocytes
TLR3 provides immediate type I IFN response following entry of stimulatory PAMPs into the CNS, as it is in HSV infection. The receptor plays a vital role in astrocytes, contributing to rapid infection sensing and suppression of viral replication, precluding the spread of virus beyond neurons. The ro...
Autores principales: | Mielcarska, Matylda B., Gregorczyk-Zboroch, Karolina P., Szulc-Dąbrowska, Lidia, Bossowska-Nowicka, Magdalena, Wyżewski, Zbigniew, Cymerys, Joanna, Chodkowski, Marcin, Kiełbik, Paula, Godlewski, Michał M., Gieryńska, Małgorzata, Toka, Felix N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705377/ https://www.ncbi.nlm.nih.gov/pubmed/33281554 http://dx.doi.org/10.3389/fncel.2020.544612 |
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