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GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria

COVID-19 pandemic has almost made hand sanitization a ritual resulting in a steep increase in the frequency of hand sanitization and an unprecedented surge in demand for hand sanitizers. In fact, several governments had to ration hand sanitizers in the retail outlets and over the counter chemist sho...

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Autores principales: Balkrishna, Acharya, Singh, Kanchan, Singh, Hoshiyar, Haldar, Swati, Varshney, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705413/
https://www.ncbi.nlm.nih.gov/pubmed/33259026
http://dx.doi.org/10.1186/s13568-020-01151-y
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author Balkrishna, Acharya
Singh, Kanchan
Singh, Hoshiyar
Haldar, Swati
Varshney, Anurag
author_facet Balkrishna, Acharya
Singh, Kanchan
Singh, Hoshiyar
Haldar, Swati
Varshney, Anurag
author_sort Balkrishna, Acharya
collection PubMed
description COVID-19 pandemic has almost made hand sanitization a ritual resulting in a steep increase in the frequency of hand sanitization and an unprecedented surge in demand for hand sanitizers. In fact, several governments had to ration hand sanitizers in the retail outlets and over the counter chemist shops. Additionally, Indian government has put a cap on the prices of hand sanitizers. Currently, large sections of global and Indian population are grappling under financial crises. Therefore, mandatory hand sanitization has made an unwelcoming, yet unavoidable addition to the already-hard-to-maintain-grocery-list. Here, we have compared the anti-microbial efficacy of Patanjali Hand Sanitizer (PHS), developed and marketed by Patanjali Ayurved Ltd. (an India-based food and herbal medicine company) with one of the topmost hand sanitizers currently used under clinical set-ups. PHS has anti-microbial efficacy comparable to that of the standard hand sanitizer. Besides, disc diffusion and time-dependent thumb print assays showed that PHS has longer retentivity on the applied surfaces, suggesting lesser consumption of the sanitizer and concomitant relaxation on the monthly grocery budget. Observed anti-bacterial potency of PHS is attributed to the disruption of bacterial cell membrane, as employed by alcohol-based hand sanitizers. A rough estimation revealed that PHS is ~ 4.3 times cost effective than the standard hand sanitizer used as the positive control in this study. Taken together, PHS is a suitable alternative for existing hand sanitizers available in the market that can relax the demand–supply strain and soften significantly the burden of monthly expenditure on hand sanitizers.
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spelling pubmed-77054132020-12-01 GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria Balkrishna, Acharya Singh, Kanchan Singh, Hoshiyar Haldar, Swati Varshney, Anurag AMB Express Original Article COVID-19 pandemic has almost made hand sanitization a ritual resulting in a steep increase in the frequency of hand sanitization and an unprecedented surge in demand for hand sanitizers. In fact, several governments had to ration hand sanitizers in the retail outlets and over the counter chemist shops. Additionally, Indian government has put a cap on the prices of hand sanitizers. Currently, large sections of global and Indian population are grappling under financial crises. Therefore, mandatory hand sanitization has made an unwelcoming, yet unavoidable addition to the already-hard-to-maintain-grocery-list. Here, we have compared the anti-microbial efficacy of Patanjali Hand Sanitizer (PHS), developed and marketed by Patanjali Ayurved Ltd. (an India-based food and herbal medicine company) with one of the topmost hand sanitizers currently used under clinical set-ups. PHS has anti-microbial efficacy comparable to that of the standard hand sanitizer. Besides, disc diffusion and time-dependent thumb print assays showed that PHS has longer retentivity on the applied surfaces, suggesting lesser consumption of the sanitizer and concomitant relaxation on the monthly grocery budget. Observed anti-bacterial potency of PHS is attributed to the disruption of bacterial cell membrane, as employed by alcohol-based hand sanitizers. A rough estimation revealed that PHS is ~ 4.3 times cost effective than the standard hand sanitizer used as the positive control in this study. Taken together, PHS is a suitable alternative for existing hand sanitizers available in the market that can relax the demand–supply strain and soften significantly the burden of monthly expenditure on hand sanitizers. Springer Berlin Heidelberg 2020-12-01 /pmc/articles/PMC7705413/ /pubmed/33259026 http://dx.doi.org/10.1186/s13568-020-01151-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Article
Balkrishna, Acharya
Singh, Kanchan
Singh, Hoshiyar
Haldar, Swati
Varshney, Anurag
GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
title GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
title_full GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
title_fullStr GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
title_full_unstemmed GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
title_short GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
title_sort germix: a skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705413/
https://www.ncbi.nlm.nih.gov/pubmed/33259026
http://dx.doi.org/10.1186/s13568-020-01151-y
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