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An in silico approach to analyze HCV genotype-specific binding-site variation and its effect on drug–protein interaction
Genotype variation in viruses can affect the response of antiviral treatment. Several studies have established approaches to determine genotype-specific variations; however, analyses to determine the effect of these variations on drug–protein interactions remain unraveled. We present an in-silico ap...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705671/ https://www.ncbi.nlm.nih.gov/pubmed/33257748 http://dx.doi.org/10.1038/s41598-020-77720-9 |