The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing

ZD55-IL-24 is similar but superior to the oncolytic adenovirus ONYX-015, yet the exact mechanism underlying the observed therapeutic effect is still not well understood. Here we sought to elucidate the underlying antitumor mechanism of ZD55-IL-24 in both immunocompetent and immunocompromised mouse m...

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Detalles Bibliográficos
Autores principales: Hu, Hai-Jun, Liang, Xiu, Li, Hai-Lang, Du, Chun-Ming, Hao, Jia-Li, Wang, Huai-Yuan, Gu, Jin-Fa, Ni, Ai-Min, Sun, Lan-Ying, Xiao, Jing, Hu, Jin-Qing, Yuan, Hao, Dai, Yan-Song, Jin, Xiao-Ting, Zhang, Kang-Jian, Liu, Xin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705698/
https://www.ncbi.nlm.nih.gov/pubmed/33257647
http://dx.doi.org/10.1038/s41419-020-03223-0

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