A randomised clinical trial of methotrexate points to possible efficacy and adaptive immune dysfunction in psychosis

NMDA autoantibody encephalitis presenting as schizophrenia suggests the possible role of adaptive cell-mediated immunity in idiopathic schizophrenia. However, to our knowledge there have been no trials of the immune-suppressant methotrexate in schizophrenia. We tested if low-dose methotrexate as use...

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Detalles Bibliográficos
Autores principales: Chaudhry, I. B., Husain, M. O., Khoso, A. B., Husain, M. I., Buch, M. H., Kiran, T., Fu, B., Bassett, P., Qurashi, I., ur Rahman, R., Baig, S., Kazmi, A., Corsi-Zuelli, F., Haddad, P. M., Deakin, B., Husain, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705702/
https://www.ncbi.nlm.nih.gov/pubmed/33257661
http://dx.doi.org/10.1038/s41398-020-01095-8

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