Cargando…

Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy

Diabetes is an independent risk factor for the development of heart failure. Increased fatty acid (FA) uptake and deranged utilization leads to reduced cardiac efficiency and accumulation of cardiotoxic lipids, which is suggested to facilitate diabetic cardiomyopathy. We studied whether reduced FA u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Umbarawan, Yogi, Kawakami, Ryo, Syamsunarno, Mas Rizky A. A., Koitabashi, Norimichi, Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Sunaga, Hiroaki, Matsui, Hiroki, Kurabayashi, Masahiko, Iso, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705707/ https://www.ncbi.nlm.nih.gov/pubmed/33257783 http://dx.doi.org/10.1038/s41598-020-77895-1

Ejemplares similares

Reduced Fatty Acid Use from CD36 Deficiency Deteriorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice
por: Umbarawan, Yogi, et al.
Publicado: (2021)

Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure
por: Umbarawan, Yogi, et al.
Publicado: (2018)

Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice
por: Umbarawan, Yogi, et al.
Publicado: (2018)

DPP-4 inhibitor induces FGF21 expression via sirtuin 1 signaling and improves myocardial energy metabolism
por: Furukawa, Nozomi, et al.
Publicado: (2020)

CD36 is indispensable for nutrient homeostasis and endurance exercise capacity during prolonged fasting
por: Iso, Tatsuya, et al.
Publicado: (2018)

Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice
por: Iso, Tatsuya, et al.
Publicado: (2019)

Fatty Acid Binding Protein 4 and 5 Play a Crucial Role in Thermogenesis under the Conditions of Fasting and Cold Stress
por: Syamsunarno, Mas Rizky A. A., et al.
Publicado: (2014)

Elongation of Long‐Chain Fatty Acid Family Member 6 (Elovl6)‐Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP‐Activated Protein Kinase/Krüppel‐Like Factor 4 (AMPK/KLF4) Signaling
por: Sunaga, Hiroaki, et al.
Publicado: (2016)

A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting
por: Syamsunarno, Mas Rizky A. A., et al.
Publicado: (2013)

Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption
por: Shrestha, Suman, et al.
Publicado: (2018)

Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts
por: Sunaga, Hiroaki, et al.
Publicado: (2019)

Ketone body and FGF21 coordinately regulate fasting-induced oxidative stress response in the heart
por: Kawakami, Ryo, et al.
Publicado: (2022)

Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes
por: Matsui, Hiroki, et al.
Publicado: (2012)

Prognostic impact of elevated fatty acid‐binding protein 1 in patients with heart failure
por: Kagami, Kazuki, et al.
Publicado: (2021)

Pathophysiological role of fatty acid‐binding protein 4 in Asian patients with heart failure and preserved ejection fraction
por: Harada, Tomonari, et al.
Publicado: (2020)

Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury
por: Kawakami, Ryo, et al.
Publicado: (2021)

Cardiac Metabolism and Contractile Function in Mice with Reduced Trans-Endothelial Fatty Acid Transport
por: Iso, Tatsuya, et al.
Publicado: (2021)

Peroxisome Proliferator‐Activated Receptor‐γ in Capillary Endothelia Promotes Fatty Acid Uptake by Heart During Long‐Term Fasting
por: Goto, Kosaku, et al.
Publicado: (2013)

Protective Effects of Caesalpinia sappan Linn. and Its Bioactive Compounds on Cardiovascular Organs
por: Syamsunarno, Mas Rizky AA, et al.
Publicado: (2021)

Ketogenic diet in action: Metabolic profiling of pyruvate dehydrogenase deficiency
por: Ogawa, Eri, et al.
Publicado: (2023)

Remarkable regression of massive deep vein thrombosis in response to intensive oral rivaroxaban treatment
por: Koitabashi, Norimichi, et al.
Publicado: (2015)

Adaptive Servo-ventilation Therapy Results in the Prevention of Arrhythmias in Patients with Heart Failure Due to Ischemic Heart Disease
por: Nagasaka, Takashi, et al.
Publicado: (2021)

Editorial: Medicinal Plants in the Treatment of Myocardial Injury and Vascular Diseases
por: Syamsunarno, Mas Rizky AA, et al.
Publicado: (2022)

Omics Biomarkers for Monitoring Tuberculosis Treatment: A Mini-Review of Recent Insights and Future Approaches
por: Pitaloka, Dian Ayu Eka, et al.
Publicado: (2022)

Nonbacterial Thrombotic Endocarditis—A Rare Case of Acute Libman-Sacks Endocarditis Complicated by Multiple Cerebral Infarcts: Case Report and Literature Review
por: Kato, Toshimitsu, et al.
Publicado: (2020)

The Potency of Moringa oleifera Lam. as Protective Agent in Cardiac Damage and Vascular Dysfunction
por: Alia, Fenty, et al.
Publicado: (2022)

Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension
por: Seki, Mitsuru, et al.
Publicado: (2019)

Effect of Inferior Vena Cava Filter on Venous Thromboembolism Mortality in Japan　― JROAD and JROAD-DPC Registry Analysis ―
por: Ohyama, Yoshiaki, et al.
Publicado: (2019)

Impact of uric acid on incident hypertension: Sex-specific analysis in different age groups
por: Ohyama, Yoshiaki, et al.
Publicado: (2019)

Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level
por: Tanaka, Yuji, et al.
Publicado: (2019)

Cost-Effectiveness of Ferrous Fumarate–Folic Acid and Ferrous Gluconate–Multivitamins in a High Prevalence Area of Iron Deficiency Anemia in Indonesia
por: Rakanita, Yasinta, et al.
Publicado: (2021)

Review of herbal medicine works in the avian species
por: Hartady, Tyagita, et al.
Publicado: (2021)

Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription
por: Tanaka, Yuji, et al.
Publicado: (2020)

Global Deletion of the Prolactin Receptor Aggravates Streptozotocin-Induced Diabetes in Mice
por: Ramirez-Hernandez, Gabriela, et al.
Publicado: (2021)

Gender-effect on the contractile properties of skeletal muscle in streptozotocin-induced diabetic rats
por: Virgen-Ortiz, Adolfo, et al.
Publicado: (2018)

Ethanol extract from Moringa oleifera leaves modulates brown adipose tissue and bone morphogenetic protein 7 in high-fat diet mice
por: Syamsunarno, Mas Rizky A. A., et al.
Publicado: (2021)

2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche
por: Koike, Naoyoshi, et al.
Publicado: (2020)

Pathophysiological and diagnostic importance of fatty acid-binding protein 1 in heart failure with preserved ejection fraction
por: Harada, Tomonari, et al.
Publicado: (2021)

Temporal Adaptive Changes in Contractility and Fatigability of Diaphragm Muscles from Streptozotocin-Diabetic Rats
por: Brotto, Marco, et al.
Publicado: (2010)

Comparative effects of long-acting and short-acting loop diuretics on cardiac sympathetic nerve activity in patients with chronic heart failure
por: Matsuo, Yae, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_a7i4cnsgk7ue04ujb1ssgv6est