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Pharmacological targeting of c-FLIP(L) and Bcl-2 family members promotes apoptosis in CD95L-resistant cells

The development of efficient combinatorial treatments is one of the key tasks in modern anti-cancer therapies. An apoptotic signal can either be induced by activation of death receptors (DR) (extrinsic pathway) or via the mitochondria (intrinsic pathway). Cancer cells are characterized by deregulati...

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Detalles Bibliográficos
Autores principales:	König, Corinna, Hillert-Richter, Laura K., Ivanisenko, Nikita V., Ivanisenko, Vladimir A., Lavrik, Inna N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705755/ https://www.ncbi.nlm.nih.gov/pubmed/33257694 http://dx.doi.org/10.1038/s41598-020-76079-1

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