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Changed reactivity of secondary hydroxy groups in C8-modified adenosine – lessons learned from silylation
Synthesis of site-specifically modified oligonucleotides has become a major tool for RNA structure and function studies. Reporter groups or specific functional entities are required to be attached at a pre-defined site of the oligomer. An attractive strategy is the incorporation of suitably function...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705864/ https://www.ncbi.nlm.nih.gov/pubmed/33299483 http://dx.doi.org/10.3762/bjoc.16.234 |