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Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes
Imidazo[1,5-a]pyridines were efficiently prepared via the cyclization of 2-picolylamines with nitroalkanes electrophilically activated in the presence of phosphorous acid in polyphosphoric acid (PPA) medium.
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705866/ https://www.ncbi.nlm.nih.gov/pubmed/33299488 http://dx.doi.org/10.3762/bjoc.16.239 |
| _version_ | 1783617036868386816 |
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| author | Aksenov, Dmitrii A Arutiunov, Nikolai A Maliuga, Vladimir V Aksenov, Alexander V Rubin, Michael |
| author_facet | Aksenov, Dmitrii A Arutiunov, Nikolai A Maliuga, Vladimir V Aksenov, Alexander V Rubin, Michael |
| author_sort | Aksenov, Dmitrii A |
| collection | PubMed |
| description | Imidazo[1,5-a]pyridines were efficiently prepared via the cyclization of 2-picolylamines with nitroalkanes electrophilically activated in the presence of phosphorous acid in polyphosphoric acid (PPA) medium. |
| format | Online Article Text |
| id | pubmed-7705866 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-77058662020-12-08 Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes Aksenov, Dmitrii A Arutiunov, Nikolai A Maliuga, Vladimir V Aksenov, Alexander V Rubin, Michael Beilstein J Org Chem Full Research Paper Imidazo[1,5-a]pyridines were efficiently prepared via the cyclization of 2-picolylamines with nitroalkanes electrophilically activated in the presence of phosphorous acid in polyphosphoric acid (PPA) medium. Beilstein-Institut 2020-11-26 /pmc/articles/PMC7705866/ /pubmed/33299488 http://dx.doi.org/10.3762/bjoc.16.239 Text en Copyright © 2020, Aksenov et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Aksenov, Dmitrii A Arutiunov, Nikolai A Maliuga, Vladimir V Aksenov, Alexander V Rubin, Michael Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes |
| title | Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes |
| title_full | Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes |
| title_fullStr | Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes |
| title_full_unstemmed | Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes |
| title_short | Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes |
| title_sort | synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705866/ https://www.ncbi.nlm.nih.gov/pubmed/33299488 http://dx.doi.org/10.3762/bjoc.16.239 |
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