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Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study

During the pandemic of COVID-19, which started in December 2019, hydroxychloroquine, the drug which was first introduced as antimalarial medication, was widely used to treat this new viral infection, and it was reported in the literature as a safe drug for use in patients with G6PD deficiency; here,...

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Detalles Bibliográficos
Autores principales: Obeidat, Khaldun, Yassin, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705928/
http://dx.doi.org/10.1159/000511688
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author Obeidat, Khaldun
Yassin, Mohamed A.
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Yassin, Mohamed A.
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description During the pandemic of COVID-19, which started in December 2019, hydroxychloroquine, the drug which was first introduced as antimalarial medication, was widely used to treat this new viral infection, and it was reported in the literature as a safe drug for use in patients with G6PD deficiency; here, we report a 64-year-old male who was started on hydroxychloroquine as treatment for COVID-19 that led to hemolysis, and further investigation showed that the patient is deficient for glucose-6-phosphate dehydrogenase.
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spelling pubmed-77059282020-12-02 Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study Obeidat, Khaldun Yassin, Mohamed A. Dubai Medical Journal Case Report During the pandemic of COVID-19, which started in December 2019, hydroxychloroquine, the drug which was first introduced as antimalarial medication, was widely used to treat this new viral infection, and it was reported in the literature as a safe drug for use in patients with G6PD deficiency; here, we report a 64-year-old male who was started on hydroxychloroquine as treatment for COVID-19 that led to hemolysis, and further investigation showed that the patient is deficient for glucose-6-phosphate dehydrogenase. S. Karger AG 2020-11-17 /pmc/articles/PMC7705928/ http://dx.doi.org/10.1159/000511688 Text en Copyright © 2020 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc-nd/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND). Usage and distribution for commercial purposes as well as any distribution of modified material requires written permission. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
spellingShingle Case Report
Obeidat, Khaldun
Yassin, Mohamed A.
Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study
title Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study
title_full Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study
title_fullStr Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study
title_full_unstemmed Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study
title_short Can Hydroxychloroquine Cause G6PD-Related Hemolysis? A Case Study
title_sort can hydroxychloroquine cause g6pd-related hemolysis? a case study
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705928/
http://dx.doi.org/10.1159/000511688
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