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BCG Vaccine does not Protect Against COVID-19

A recent article by Jop de Vrieze (March 23, 2020) suggested that BCG vaccine could protect against COVID-19 infections. The arguments were that several European countries, like Italy, Spain, France, and Germany, which are badly affected by COVID-19, and the USA stopped vaccination of the general po...

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Autores principales: Allam, Mohamed F., Amin, Ghada E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705950/
https://www.ncbi.nlm.nih.gov/pubmed/33299492
http://dx.doi.org/10.2174/1874306402014010045
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author Allam, Mohamed F.
Amin, Ghada E.
author_facet Allam, Mohamed F.
Amin, Ghada E.
author_sort Allam, Mohamed F.
collection PubMed
description A recent article by Jop de Vrieze (March 23, 2020) suggested that BCG vaccine could protect against COVID-19 infections. The arguments were that several European countries, like Italy, Spain, France, and Germany, which are badly affected by COVID-19, and the USA stopped vaccination of the general population by BCG and excluded it from their routine vaccination schedule. Many people started to receive doses of BCG based on that hypothesis even before its confirmation. We think that the BCG vaccine could not protect against COVID-19 because several countries like China and Iran, which are severely affected by COVID-19, still include the BCG vaccine in its routine vaccination schedule. Other arguments include that the BCG vaccine improves cell-mediated immunity with little effect on humoral immunity; Immunity against viruses, in general, is mainly humoral.
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spelling pubmed-77059502020-12-08 BCG Vaccine does not Protect Against COVID-19 Allam, Mohamed F. Amin, Ghada E. Open Respir Med J Respiratory Medicine A recent article by Jop de Vrieze (March 23, 2020) suggested that BCG vaccine could protect against COVID-19 infections. The arguments were that several European countries, like Italy, Spain, France, and Germany, which are badly affected by COVID-19, and the USA stopped vaccination of the general population by BCG and excluded it from their routine vaccination schedule. Many people started to receive doses of BCG based on that hypothesis even before its confirmation. We think that the BCG vaccine could not protect against COVID-19 because several countries like China and Iran, which are severely affected by COVID-19, still include the BCG vaccine in its routine vaccination schedule. Other arguments include that the BCG vaccine improves cell-mediated immunity with little effect on humoral immunity; Immunity against viruses, in general, is mainly humoral. Bentham Science Publishers 2020-11-26 /pmc/articles/PMC7705950/ /pubmed/33299492 http://dx.doi.org/10.2174/1874306402014010045 Text en © 2020 Allam & Amin. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Respiratory Medicine
Allam, Mohamed F.
Amin, Ghada E.
BCG Vaccine does not Protect Against COVID-19
title BCG Vaccine does not Protect Against COVID-19
title_full BCG Vaccine does not Protect Against COVID-19
title_fullStr BCG Vaccine does not Protect Against COVID-19
title_full_unstemmed BCG Vaccine does not Protect Against COVID-19
title_short BCG Vaccine does not Protect Against COVID-19
title_sort bcg vaccine does not protect against covid-19
topic Respiratory Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705950/
https://www.ncbi.nlm.nih.gov/pubmed/33299492
http://dx.doi.org/10.2174/1874306402014010045
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