Cargando…
Metformin treatment of high-fat diet-fed obese male mice restores sperm function and fetal growth, without requiring weight loss
Male obesity is associated with subfertility and increased disease risk of offspring. It is unknown if effects can be reversed through pharmacological interventions. Five- to 6-week-old C57BL6 male mice were fed control diet (n = 10, CD) or high-fat diet (n = 20, HFD) for 16 weeks. Animals fed with...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705976/ https://www.ncbi.nlm.nih.gov/pubmed/32098932 http://dx.doi.org/10.4103/aja.aja_141_19 |