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AMPK-SIRT1 pathway dysfunction contributes to neuron apoptosis and cognitive impairment induced by sevoflurane

The anesthetic sevoflurane (Sev) is widely used because of its low blood-gas partition coefficient and lack of pungency. However, the application of Sevmay lead to cognitive impairment later in life. Previous results have indicated that exposure to Sev-induced neuronal apoptosis and cognitive dysfun...

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Detalles Bibliográficos
Autores principales: Liu, Liwei, Liu, Chao, Fang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706003/
https://www.ncbi.nlm.nih.gov/pubmed/33200801
http://dx.doi.org/10.3892/mmr.2020.11694