Cargando…
Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway
BACKGROUND: Autophagy plays an essential role in metastasis of malignancies. Although our studies showed that Aurora-B facilitate pulmonary metastasis in OS, the mechanism of Aurora-B kinase on autophagy and metastasis in OS has not been explored. METHODS: Clinical-pathological parameters and follow...
Autores principales: | Wu, Xin, Liu, Jia-ming, Song, Hong-hai, Yang, Qi-kun, Ying, Hui, Tong, Wei-lai, Zhou, Yang, Liu, Zhi-li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706191/ https://www.ncbi.nlm.nih.gov/pubmed/33292257 http://dx.doi.org/10.1186/s12935-020-01674-1 |
Ejemplares similares
-
Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway
por: Wang, Jiwei, et al.
Publicado: (2016) -
Silencing of SNHG6 induced cell autophagy by targeting miR-26a-5p/ULK1 signaling pathway in human osteosarcoma
por: Zhu, Xin, et al.
Publicado: (2019) -
YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas
por: Xu, Wei, et al.
Publicado: (2021) -
Echovirus induces autophagy to promote viral replication via regulating mTOR/ULK1 signaling pathway
por: Wu, Chunchen, et al.
Publicado: (2023) -
Blocking AMPK/ULK1-dependent autophagy promoted apoptosis and suppressed colon cancer growth
por: Liu, Jing, et al.
Publicado: (2019)