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The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex

BACKGROUND: The histone methyltransferase SETDB1 (also known as ESET) represses genes and various types of transposable elements, such as endogenous retroviruses (ERVs) and integrated exogenous retroviruses, through a deposition of trimethylation on lysine 9 of histone H3 (H3K9me3) in mouse embryoni...

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Detalles Bibliográficos
Autores principales: Tsusaka, Takeshi, Fukuda, Kei, Shimura, Chikako, Kato, Masaki, Shinkai, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706265/
https://www.ncbi.nlm.nih.gov/pubmed/33256805
http://dx.doi.org/10.1186/s13072-020-00374-4