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The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex
BACKGROUND: The histone methyltransferase SETDB1 (also known as ESET) represses genes and various types of transposable elements, such as endogenous retroviruses (ERVs) and integrated exogenous retroviruses, through a deposition of trimethylation on lysine 9 of histone H3 (H3K9me3) in mouse embryoni...
Autores principales: | Tsusaka, Takeshi, Fukuda, Kei, Shimura, Chikako, Kato, Masaki, Shinkai, Yoichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706265/ https://www.ncbi.nlm.nih.gov/pubmed/33256805 http://dx.doi.org/10.1186/s13072-020-00374-4 |
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