Randomized clinical trial to compare efficacy and safety of repeated courses of rituximab to single-course rituximab followed by maintenance mycophenolate-mofetil in children with steroid dependent nephrotic syndrome

BACKGROUND: Approximately 30% of children with idiopathic nephrotic syndrome develop a complicated course with frequent relapses or steroid dependency. Rituximab, a B cell depleting monoclonal antibody, is a safe and effective alternative to steroids or other immunosuppressants for achieving and mai...

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Detalles Bibliográficos
Autores principales: Basu, Biswanath, Preussler, Stella, Sander, Anja, Mahapatra, T. K. S., Schaefer, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706288/
https://www.ncbi.nlm.nih.gov/pubmed/33256621
http://dx.doi.org/10.1186/s12882-020-02153-5

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