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A new role for the synaptonemal complex in the regulation of meiotic recombination
Proper segregation during meiosis requires that homologs be connected by the combination of crossovers and sister chromatid cohesion. To generate crossovers, numerous double-strand breaks (DSBs) are introduced throughout the genome by the conserved Spo11 endonuclease. DSB formation and its repair ar...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706701/ https://www.ncbi.nlm.nih.gov/pubmed/33262143 http://dx.doi.org/10.1101/gad.345488.120 |